Effects of Process-Based Cognitive Training on Memory in the Healthy Elderly and Patients with Mild Cognitive Impairment: A Randomized Controlled Trial

Shin, Moon Sam; Lee, Ahee; Cho, A Young; Son, Mi-Nam; Kim, Yun-Hee

doi:10.30773/pi.2019.0225

Cited by 7 publications

(4 citation statements)

References 52 publications

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“…Memory is a complex and multifaceted cognitive domain that is most commonly affected in cases of MCI (25). Gathering or assimilating new information not only requires the ability to store but also the use of strategies aimed at facilitating the memorization process.…”

Section: Discussionmentioning

confidence: 99%

Neurocognitive function in procedures correcting severe aortic valve stenosis: patterns and determinants

Ranucci,

Brischigiaro,

Mazzotta

et al. 2024

Front. Cardiovasc. Med.

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BackgroundNeurocognitive changes occurring after a surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) procedure for the correction of severe aortic stenosis (AS) have not been widely addressed and, if addressed, have produced conflicting results. The purpose of this study is to identify the pre-procedural neurocognitive pattern and its determinants in a setting of elderly (>65 years) patients with severe AS undergoing SAVR or TAVI and the changes occurring at a 2–3 month follow-up.MethodsThis was a prospective cohort study included in the Italian Registry on Outcomes in Aortic Stenosis Treatment in Elderly Patients. Patients were assessed both before and after (2–3 months) the procedure using the Montreal Cognitive Assessment (MoCA) test. Data on periprocedural demographics, clinical factors, and outcome measures were collected.ResultsBefore the procedure, 70% of the patients demonstrated a MoCA score <23 points, which was indicative of cognitive dysfunction. The factors associated with neurocognitive dysfunction were age, functional capacity, chronic heart failure, and hemoglobin levels. After the procedure, there was an overall improvement in the MoCA score of the patients, but 28% of the patients showed a reliable worsening of their condition. The factors associated with MoCA worsening were platelet transfusions and the amount of red blood cell units transfused.ConclusionThe correction of severe AS leads to an improvement in neurocognitive function after 2–3 months. This improvement does not differentiate between SAVR and TAVI after matching for pre-procedural factors. The only modifiable factor associated with pre-procedural neurocognitive function is anemia, and anemia correction with red blood cell transfusions is associated with a worsening of neurocognitive function. This leads to the hypothesis that anemia correction before the procedure (with iron and/or erythropoietin) may limit the risk of a post-procedural worsening of neurocognitive function.

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Section: Discussionmentioning

confidence: 99%

Neurocognitive function in procedures correcting severe aortic valve stenosis: patterns and determinants

Ranucci,

Brischigiaro,

Mazzotta

et al. 2024

Front. Cardiovasc. Med.

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“…Many studies have shown that cognitive activity can reduce depressive symptoms in patients with MCI and dementia (Chan et al., 2020; De et al., 2016). One study has shown that cognitive activity can improve the depressive symptoms of patients with MCI and dementia by breaking the vicious circle of negative thinking (Shin et al., 2020). Accordingly, a combination of physical and cognitive activities can maximize the roles of both.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of nonpharmacological multi‐component intervention on depressive symptoms in patients with mild cognitive impairment and dementia: A systematic review and meta‐analysis

Cai,

Bai,

Hou

et al. 2023

Int J Mental Health Nurs

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Patients with mild cognitive impairment (MCI) and dementia are more prone to depression than people without MCI or dementia. Some studies have found nonpharmacological multi‐component intervention to be more effective than single‐component intervention in improving the condition of patients with MCI and dementia; however, their effect on depressive symptoms is still inconsistent. Therefore, it is necessary to explore the effectiveness of nonpharmacological multi‐component intervention in improving depressive symptoms in patients with MCI and dementia. This review retrieved papers from PubMed, Embase, Cochrane Library, CINAHL, PsycINFO and CNKI. The retrieval time limit was set from 1 January 1990 to 25 November 2022. The PRISMA 2020 guideline was used to report the included studies. The result showed that nonpharmacological multi‐component intervention could improve depressive symptoms in patients with MCI and dementia. Among them, nonpharmacological multi‐component intervention with a duration of <6 months, physical and cognitive activities, or other activities had significant effects. However, each study differed in terms of specific measures, duration and frequency of intervention methods. Accordingly, more randomized controlled trials with larger samples are required to discover the best scheme for nonpharmacological multi‐component intervention.

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“…Previous studies suggested that cognitive training is a potentially effective way to improve EF in older adults with MCI [ 6 , 7 ]. Two recent studies suggest that process-based cognitive training focusing primarily EF is particularly effective among the various training approaches [ 8 , 9 ]. Process-based cognitive training refers to the repetitive practice of computerized and/or manual cognitive tasks without explicit strategies [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…Two recent studies suggest that process-based cognitive training focusing primarily EF is particularly effective among the various training approaches [ 8 , 9 ]. Process-based cognitive training refers to the repetitive practice of computerized and/or manual cognitive tasks without explicit strategies [ 8 , 9 ]. Several studies provided evidence to support the effectiveness of process-based cognitive training in enhancing EF among both younger and older individuals [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Transferability and sustainability of process-based multi-task adaptive cognitive training in community-dwelling older adults with mild cognitive impairment: a randomized controlled trial

Zhao

Zhang³

et al. 2023

BMC Psychiatry

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Background Cognitive training shows promising effects for improving cognitive domains in individuals with mild cognitive impairment (MCI), including the crucial predictive factor of executive function (EF) for dementia prognosis. Few studies have paid sufficient emphasis on the training-induced effects of cognitive training programs, particularly with regards to targeting EF. A process-based multi-task adaptive cognitive training (P-bM-tACT) program targeting EF is required to examine direct, transfer, and sustainability effects in older adults with MCI. Objective This study aimed to evaluate the direct effects of a P-bM-tACT program on EF, the transfer effects on untrained cognitive domains, and further explore the sustainability of training gains for older adults with MCI in the community. Methods In a single-blind, randomized controlled trial, 92 participants with MCI were randomly assigned to either the intervention group, participating in a P-bM-tACT program (3 training sessions/week, 60 min/session for 10 weeks) or the wait-list control group, accepting a health education program on MCI (1 education session/ twice a week, 40–60 min/session for 10 weeks). The direct and transfer effects of the P-bM-tACT program were assessed at baseline, immediately after 10 weeks of training, and the 3-month follow-up. Repeated measures analysis of variance and a simple effect test were used to compare the direct and transfer effects over the 3-time points between the two groups. Results The P-bM-tACT program yielded a greater benefit of direct and transfer effects in the intervention group participants than in the wait-list control group. Combined with the results of simple effect tests, the direct and transfer effects of participants in the intervention group significantly increased immediately after 10 weeks of training compared to the baseline (F = 14.702 ~ 62.905, p < 0.05), and these effects were maintained at the 3-month follow-up (F = 19.595 ~ 122.22, p < 0.05). Besides, the acceptability of the cognitive training program was established with a high adherence rate of 83.4%. Conclusions The P-bM-tACT program exerted positive direct and transfer effects on the improvement of cognitive function, and these effects were sustained for 3 months. The findings provided a viable and potential approach to improving cognitive function in older adults with MCI in the community. Trial registration The trial was registered at Chinese Clinical Trials Registry on 09/01/2019 (www.chictr.org.cn; Number Registry: ChiCTR1900020585).

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Effects of Process-Based Cognitive Training on Memory in the Healthy Elderly and Patients with Mild Cognitive Impairment: A Randomized Controlled Trial

Cited by 7 publications

References 52 publications

Neurocognitive function in procedures correcting severe aortic valve stenosis: patterns and determinants

Neurocognitive function in procedures correcting severe aortic valve stenosis: patterns and determinants

Effectiveness of nonpharmacological multi‐component intervention on depressive symptoms in patients with mild cognitive impairment and dementia: A systematic review and meta‐analysis

Transferability and sustainability of process-based multi-task adaptive cognitive training in community-dwelling older adults with mild cognitive impairment: a randomized controlled trial

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