Effects of probiotics and application methods on performance and response of broiler chickens to an Eimeria challenge

Ritzi, Miranda M.; Abdelrahman, Wael; Mohnl, M.; Dalloul, Rami A.

doi:10.3382/ps.2014-04207

Cited by 128 publications

(98 citation statements)

References 25 publications

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“…The results of this study suggest that the combination of probiotics and coccidiosis vaccine can, when compared to untreated controls, result in better performance and intestinal response. Early establishment of beneficial microbiota by probiotics can inhibit pathogens thus potentiating a protective effect and enhancing host resistance to infection while reducing the need for prophylactic drug usage [5, 19, 38]. As PoultryStar is a product that contains multiple probiotic species of bacteria, there is a greater potential that such probiotics can be active in a wider range of conditions, similar to other multi-strain probiotics, resulting in greater efficacy [3, 39].…”

Section: Discussionmentioning

confidence: 99%

“…The potential consequences of coccidiosis vaccine administration at a young age could be overcome by proper and uniform delivery of the vaccine, as well as the chick having a healthy intestinal tract colonized by a normal pathogen-free microbiota [13, 15]. Probiotics have the potential to enhance host defenses and affect the digestive microbiota positively, while protecting against colonization by harmful bacteria and maintaining intestinal integrity [13, 15, 17–19]. Based on these findings, probiotics may be able to attenuate the negative consequences of early vaccine administration.…”

Section: Introductionmentioning

confidence: 99%

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Combination of probiotics and coccidiosis vaccine enhances protection against an Eimeria challenge

Ritzi

Abdelrahman

Van-Heerden

et al. 2016

Vet Res

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Coccidiosis is endemic in the commercial broiler industry capable of inflicting devastating economic losses to poultry operations. Vaccines are relatively effective in controlling the disease; their efficacy could potentially be improved with concurrent use of probiotics as evaluated in this study using an Eimeria challenge. Day of hatch 400 Cobb-500 male broilers were assigned to one of four treatment groups including control (CON), vaccine-only gel application (VNC), probiotic-only gel application (NPC), and vaccine-plus-probiotic gel application (VPC). Birds were placed in floor pens (6 replicate pens/treatment, 16–17 birds/pen). NPC and VPC birds received the probiotics in the water on days 2–4, 8, 14–20, 22, 29, and 34–36. On day 15, birds were mildly challenged with 0.5 mL of a mixed oral inoculum of Eimeria sp. prepared with the coccidiosis vaccine at 10× the vaccination dose. Performance measurements were recorded on first day and weekly afterwards, and lesion scores were evaluated 6 days post-challenge. Overall, the probiotics and coccidiosis vaccine resulted in an enhanced protective effect against the challenge, with VPC birds exhibiting lower lesion scores in the duodenum than VNC or NPC birds. Birds in the VPC treatment also demonstrated higher weight gains during days 1–15, days 7–15, and days 21–28 when compared to the VNC birds. These results suggest that the combination of probiotics and coccidiosis vaccines could enhance performance and provide an additional protective effect against a mixed Eimeria challenge.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Combination of probiotics and coccidiosis vaccine enhances protection against an Eimeria challenge

Ritzi

Abdelrahman

Van-Heerden

et al. 2016

Vet Res

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“…Probiotics also influenced humoral and cell-mediated immune responses by increasing antibody production and upregulating T lymphocyte numbers and associated responses [15][16][17]. Probiotics have proven their ability to enhance the immune response by promoting the clearance of several economically important pathogens such as Eimeria spp., Salmonella spp., Escherichia coli and Clostridium perfringens, further asserting their potential use as an antibiotic alternative [6,[18][19][20].…”

Section: Introductionmentioning

confidence: 99%

In ovo and Dietary Supplementation of Probiotics Affects Post-Hatch Expression of Immune-Related Genes in Broiler Chicks

Pender¹,

Kim²,

Sumners³

et al. 2017

J immuno Biol

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During the first week post-hatch, the neonatal chick is immunologically vulnerable and subject to infectious threats found in the environment. Probiotics are live, non-pathogenic microorganisms known to have a positive effect on the host by improving the natural balance of gut microbiota and promoting animal health. The objective of this study was to determine the effects of administering probiotics in ovo and in the diet on broiler chick hatchability, and post-hatch immune organ weights and ileal immune-related gene expression. At embryonic day 18, 1584 eggs were injected with nothing (Dry), 1 × 10 6 , or 1 × 10 7 (P1 and P2 respectively) probiotic bacteria. The remaining 393 eggs were left non-injected to serve as a negative control. Immune organ weights and tissue samples were taken on DOH and d4, 6, 8, 14, and 20. No differences were observed for hatchability or relative bursa weights. Only on d6, the P2 birds receiving the probiotic-supplemented diet had larger spleens as a result of a 2-way interaction between in ovo treatment and post-hatch diet. Both in ovo and dietary administration of probiotics were able to modulate the expression of the immune-related genes in the ileum; however, expression patterns differed based on the gene, treatment, and time point evaluated. In conclusion, these results indicate that in ovo supplementation of this commercial probiotic product does not influence hatchability and is capable of differentially modulating expression of certain genes in the ileum. Furthermore, in ovo administration of probiotics has an effect similar to that of dietary supplementation endorsing its usage to potentially promote early colonization of beneficial bacteria to stimulate intestinal and immune system development.

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“…The performance improvements seen in SYNBIO were previously reported by Eckert et al, 2010. Enhanced performance promoted by synbiotic products may be related to the improvement in nutrient absorption, reduction of pathogens colonization, and stimulation of the immune response [19,24,25].…”

Section: Discussionmentioning

confidence: 99%

Comparative of probiotics reveals cecal microbial component associated with performance parameters in broilers

Murugesan¹

2019

Preprint

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29 Probiotics have become increasingly popular in poultry industry as a promising nutritional 30 intervention to promote modulation of intestinal microbiota as a means of improving health and 31 performance. This study aimed to determine the effects of different probiotic formulations on the 32 cecal microbial communities and performance in 21 and 42 day-old-broilers, as well as to define 33 associations between ceca microbial profile and growth parameters. Probiotics investigated 34 included a synbiotic (SYNBIO), a yeast-based probiotic (YEAST), and three single-strain 35 formulations of spore-forming Bacillus amyloliquefaciens (SINGLE1), B. subtilis (SINGLE2) 36 and B. licheniformis (SINGLE3). Dietary inclusion of SYNBIO, YEAST, and SINGLE2 37 increased body weight (BW) by 7, 14, and 21d (p<0.05) compared to a basal diet without 38 probiotics (CON). The treatments SYNBIO, and YEAST decreased mortality by 21d, while 39 SYNBIO reduced the overall mortality rate by 42d (p<0.05). Bifidobacteriales had the highest 40 (p<0.05) population in SINGLE2, whereas Clostridiales was reduced compared to CON, 41 SINGLE1, and SINGLE3. The addition of SYNBIO into diet mainly stimulated (p<0.05) the 42 cecal relative abundance of Lactobacillales by 21d. Besides, Spearman's correlation analyses 43 revealed that population of Lactobacillales was associated with lower Enterobacteriales, higher 44 BW, and lower mortality of growing broilers. These results suggest that the modulation of ceca 45 microbiota and the greatest productive parameters were achieved by supplementation of specific 46 probiotic mixture. The selection of probiotics by their ability to drive cecal microbiota towards 47 lactic acid bacteria colonization may be a strategic approach to improve the indicators of 48 performance in broilers. 49 3 50 51 Introduction 52 Worldwide, the decreased percentage of chickens treated with sub-therapeutic levels of 53 antibiotics has attracted attention towards a better understanding of dietary alternatives as growth 54 and health promoters. Among them, probiotics have been indicated as a promising nutritional 55 intervention to manipulate the avian microbiome [1-4]. Beneficial bacteria colonization of 56 intestinal microbiota is essential for favoring host growth and performance, while an unfavorable 57 alteration of the commensal structure may promote enteric infections, thereby deteriorating 58 welfare and the performance indicators of poultry production [5]. 59 Probiotics have become increasingly popular across human medicine and livestock 60 industry due to the following benefits in the host: stimulation of beneficial microbiota, reduction, 61 and prevention of pathogen colonization, development of immune system, improvement in 62 digestive efficiency, and maturation of intestinal microbiota [3,5-9]. Although several bacterial 63 species and yeasts have been described as potential probiotic for broiler chickens; Bacillus, 64 Lactobacillus, Enterococcus, Bifidobacterium, Pediococcus, and Escherichia are the most 65 common bacte...

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Effects of probiotics and application methods on performance and response of broiler chickens to an Eimeria challenge

Cited by 128 publications

References 25 publications

Combination of probiotics and coccidiosis vaccine enhances protection against an Eimeria challenge

Combination of probiotics and coccidiosis vaccine enhances protection against an Eimeria challenge

In ovo and Dietary Supplementation of Probiotics Affects Post-Hatch Expression of Immune-Related Genes in Broiler Chicks

Comparative of probiotics reveals cecal microbial component associated with performance parameters in broilers

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