“…Cocaine exposure in utero results in molecular and cellular changes in several brain areas known to be involved in memory and attention, such as caudate nucleus (Harvey et al, 2001), prefrontal cortex (Morrow et al, 2002(Morrow et al, , 2007, and hippocampus (Little and Teyler, 1996;Harvey et al, 2001;Morrow et al, 2002Morrow et al, , 2007. For example, cocaine exposure in utero results in anatomical changes in the prefrontal cortex of postnatal rats, including a loss of inhibitory projections from parvalbumin-containing GABAergic local circuit neurons to prelimbic pyramidal neurons (Morrow et al, 2005), deficient inhibitory axoaxonic synapses on pyramidal cells (Morrow et al, 2003), and an increased number of spine synapses (Morrow et al, 2007).…”