“…Previous findings have shown that prenatal exposure to CO, at concentrations (75–150 p.p.m.) below those associated with gross malformations and/or overt neurotoxic effects, induces a variety of neurobehavioural abnormalities in rat offspring including lower behavioural activity levels through preweaning, delayed development of homing behaviour and negative geotaxis, altered ontogeny of emotional responsiveness and permanent cognitive deficits (Fechter & Annau, 1977, 1980; Mactutus & Fechter, 1984, 1985; Di Giovanni et al , 1993; De Salvia et al , 1995).…”