Effects of pore shape and porosity on the properties of porous LNKN ceramics as bone substitute

Wang, Qi; Chen, Qiang; Zhu, Jianguo; Huang, Chunpeng; Darvell, B.W.; Chen, Zhiqing

doi:10.1016/j.matchemphys.2007.12.022

Cited by 36 publications

(17 citation statements)

References 8 publications

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“…While it was expected that, at 4 weeks, there would have been some resistance to push the implant free, it was unanticipated that complete fusion would have already taken place. Microporosity, macroporosity, pore size and pore shape all play important roles in the joining of the bone-implant boundary [13,36,37]. Studies have demonstrated that anywhere between 100μm and 1000μm is sufficient for bone ingrowth [38].…”

Section: 0 Discussionmentioning

confidence: 99%

SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo

2013

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Calcium phosphate (CaP) scaffolds with three dimensionally (3D) interconnected pores play an important role in mechanical interlocking and biological fixation in bone implant applications. CaPs alone, however, are only osteoconductive (ability to guide bone growth). Much attention has been given to the incorporation of biologics and pharmacologics to add osteoinductive (ability to cause new bone growth) properties to CaP materials. Because biologics and pharmacologics are generally delicate compounds and also subject to increased regulatory scrutiny, there is a need to investigate alternative methods to introduce osteoinductivity to CaP materials. In this study silica (SiO2) and zinc oxide (ZnO) have been incorporated in to 3D printed β-tricalcium phosphate (TCP) scaffolds to investigate their potential to trigger osteoinduction in vivo. Silicon and zinc are trace elements that are common to bone and have also been shown to have many beneficial properties from increased bone regeneration to angiogenesis. Implants were placed in bicortical femur defects introduced to a murine model for up to 16 weeks. Addition of dopants into TCP increased the capacity for new early bone formation by modulating collagen I production and osteocalcin production. Neovascularization was found to be up to three times more than the pure TCP control group. The findings from this study indicate that the combination of SiO2 and ZnO dopants in TCP may be a viable alternative to introduce osteoinductive properties to CaPs.

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Section: 0 Discussionmentioning

confidence: 99%

SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo

2013

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“…wettability nature same as hydroxyapatite and interconnected pores apt for cell infiltration. In comparison, AOM derived ceramics showed the best pore size and structures, and relatively good piezoelectric properties implying a promising piezoelectric composite used as bone substitute [95,96]. Work on porous lead free piezoelectric are being less reported.…”

Section: Bone Substitutementioning

confidence: 98%

A Concise Review Encircling Lead Free Porous Piezoelectric Ceramics

Pinheiro

Thenmuhil

2019

Acta Phys. Pol. A

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Lead free porous piezoelectric ceramics have been the motivation behind research by numerous scientists in perspective of environmental friendly, less dense, wide performance advantages over monolithic and polymer piezoelectric materials with enhanced figure of merit. In this review, a collective entity regarding the processing of porous piezoelectric compounds by various methods, lead free piezoelectric families like BaTiO3 (BT), Ba1−xCaxTi1−y ZryO3 (BCZT), (Bi0.5Na0.5)TiO3 (BNT), (K0.5Na0.5)NbO3 (KNN) and their solid solutions are reported. Porosity configuration, pore forming agents, and various applications in porous lead free piezoelectric ceramic have also been discussed. This review herein has discussed in terms of the tendency to work with lead free porous piezoelectric ceramics.

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“…A large amount of research has been carried out involving various manufacturing techniques to produce porous piezoelectric ceramics [17][18][19][20][21][22][23]. Different authors [24][25][26][27][28][29][30][31] developed experimental models to study the effects of pore size, porosity and sintering behaviour on the piezoelectric properties of PPMs. Gomez & Montero [32,33] introduced a new theoretical frame to study the characteristics of porous piezoelectric ceramics and 0-3/3-3 connectivity piezoelectric composites and governing equations were also derived.…”

Section: Introductionmentioning

confidence: 99%

Decoupling of plane waves in porous piezoelectric materials

Vashishth

Gupta

2014

Proc. R. Soc. A.

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In this paper, the analytical and numerical studies of two-dimensional wave propagation in porous piezoelectric materials (PPMs) are carried out. The decoupling of waves, in such materials for various crystal classes, is studied analytically for different coordinate planes. It is found that, for wave propagation in a plane, the system is decoupled in some crystal classes, whereas it remains coupled in other crystal classes. It is established that the decoupled pure-shear wave, propagating in a PPM, can be stiffened or unstiffened with piezoelectric effects even if the PPM belongs to the same symmetry group but has a different crystal class. The skewing angles and mutual angles between the polarization directions of different waves are also computed numerically.

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Effects of pore shape and porosity on the properties of porous LNKN ceramics as bone substitute

Cited by 36 publications

References 8 publications

SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo

SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo

A Concise Review Encircling Lead Free Porous Piezoelectric Ceramics

Decoupling of plane waves in porous piezoelectric materials

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