“…In contrast to the report of Bueding, Liu & Rogers (1972), it was claimed that the female S. haematobium is more sensitive than the male to metrifonate (Gear, 1976). Selectivity for schistosome acetylcholinesterase has been obtained with some dansylated acetylcholine analogues (Hillman, Chu & Dotson, 1980;Dotson, Chu & Hillman, 1981), phosphonium compounds (Willcockson, Dotson, McAllister, Grim, Ahmed & Hillman, 1982) and iV-chloroethylacetylcholine derivatives . The labelling of schistosomes with the dansylated drug is inhibited by cholinesterase inhibitors, high concentrations of atropine and mecamylamine (suggesting a low nicotinic potency), trifluoperazine and hycanthone (Hillman, Gibler & Anderson, 1978).…”