Effects of Periodontal Therapy on Circulating Oxidative Stress

Tomofuji, Takaaki; Ekuni, Daisuke; Morita, Manabu

doi:10.1007/978-1-4614-9557-4_10

Cited by 2 publications

(2 citation statements)

References 52 publications

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“…The scaling and root surface debridement has shown an improvement of serum MDA level after 30 days in all groups compared to their respective baseline values. Similar effects of improvement and a significant reduction in MDA level after scaling and root surface debridement have been reported by studies Wei et al, 36 Aziz et al, 37 and Tomofuji et al 38 The gain of improvement in MDA level in group A and B was non-significant, due to the green tea catechins that increase in the activity of superoxide dismutase and glutathione peroxidase enzyme, this lead to reduction in lipid peroxidation markers in the liver, serum, and brain. 39 Similarly, in group B, attributed to the anti-inflammatory antimicrobial effect of CHX which prevent the recolonization of putative pathogenic bacteria by creating a bacteriostatic mileu.…”

Section: Discussionsupporting

confidence: 86%

Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis

Mustafa

Baban

2019

EDJ

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Background and objectives: Periodontal disease is the most common disease associated with microbial infection with the destruction of supporting structures. This study was carried out to evaluate the effectiveness of green tea as a mouthwash in the management of chronic periodontitis in comparison to chlorhexidine mouthwash. Patients and methods: A randomized controlled trial on 45 healthy humans with mild to moderate localized chronic periodontitis. They were randomly assigned into 3 equal groups (15 patients each), and they all received scaling and root surface debridement treatments. Group A used prepared green tea 5% as mouth wash for 2 weeks, group B used chlorhexidine mouthwash 0.12% for 2 weeks and group C did not use any mouth wash. Intra-oral clinical examination and blood samples collection were done for all patients for estimating the biochemical parameters C-reactive protein, alkaline phosphatase, Malondialdehyde at baseline and 30 days after periodontal therapy. For statistical analysis, SPSS program was used. Results: The study groups showed significant reduction in clinical periodontal parameters and inflammatory markers after 30 days of periodontal therapy (P<0.001). A significant difference was seen between group A and group B in relation to clinical periodontal parameters and inflammatory markers after periodontal therapy P<0.05, while the difference between group B and group C was non-significant in relation to gingival index, clinical attachment level, C-reactive protein, alkaline phosphatase, and Malondialdehyde. Conclusion: Green tea as a mouthwash could be an appropriate and effective choice as an adjunctive measure in the treatment of chronic periodontitis.

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Section: Discussionsupporting

confidence: 86%

Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis

Mustafa

Baban

2019

EDJ

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“…Periodontal disease (PD) is a chronic inflammatory disorder that affects 10-15% of the world population and is considered the greatest cause of tooth loss, causing damage to all the structures that support the teeth: periodontal ligament, root cement, alveolar bone, and gingival tissues [1][2][3][4]. Its clinical classification is based on the presence or absence of signs of inflammation, periodontal pocket depth, gingival attachment loss, and bone loss [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Assessment of 8-Hydroxy 2-Deoxyguanosine as Salivary Biomarker for Periodontitis Patients with or without Diabetes Mellitus

Jeevitha

Jayaraman

2021

JPRI

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Aim: The aim of this study is to assess the levels of 8-hydroxy-2 deoxyguanosine as a salivary biomarker for periodontitis with or without diabetes mellitus. Study Design: Cross-sectional study Materials and Methods: 30 patients were included in the study and were categorised into three groups: periodontal health (Group a), patients with periodontitis without diabetes mellitus (Group b) and patients with periodontitis only (Group c). Unstimulated salivary samples were taken. The OHdG concentration was evaluated using Sandwich-enzyme linked immunosorbent assay by commercially available human OHdG 96 well ELISA kit. The data were statistically analysed by One-Way -ANOVA. The Newman-Keuls multiple comparison test was used to test the significance at the levels of p<0.05. Results: Salivary OHdG concentration in periodontal health, periodontitis with diabetes mellitus (P+DM), Periodontitis only (P) were analysed. Salivary OHdG concentration was found to be significantly higher (p<0.05) in periodontitis with diabetes mellitus (38±2.82 ng/L) when compared with periodontitis only (20.5±2.12 ng/L) and also when compared with healthy controls (11.5±2.12 ng/L). Conclusion: Diabetic patients with periodontitis have increased 8 hydroxy 2 deoxyguanosine than non-diabetic counterparts. Thus salivary 8 hydroxy 2 deoxyguanosine is an effective non-invasive biomarker to assess periodontitis among patients.

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Effects of Periodontal Therapy on Circulating Oxidative Stress

Cited by 2 publications

References 52 publications

Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis

Efficacy of green tea mouth wash as an adjunct to non-surgical periodontal treatment in patients with chronic periodontitis

Assessment of 8-Hydroxy 2-Deoxyguanosine as Salivary Biomarker for Periodontitis Patients with or without Diabetes Mellitus

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