Effects of Percutaneous Coronary Intervention on Depressive Symptoms in Chronic Stable Angina Patients

Abstract

ObjectiveDepression is present in 1 of 5 outpatients with coronary artery disease (CAD), and a well-documented risk factor for recurrent cardiac events and mortality. We examined the impact of percutaneous coronary intervention (PCI), on depressive symptoms, in chronic stable angina (CSA) patients.MethodsOn prospective and non-randomized trial, consecutive CSA patients (n=171), who had undergone coronary angiography from January 2006 to December 2007, were included. Patients were subdivided into PCI and non-PCI groups, and then completed 21-item the Beck Depression Inventory II (BDI-II), at the baseline and pre-discharge, to assess the depressive symptoms.ResultsA total of 108 (63%) patients were assigned to the non-PCI group, and 63 (37%) patients to the PCI group. Using an independent t-test, we found that patients with PCI were significantly older (non-PCI vs. PCI; 57±11 vs. 64±10, years, p<0.001), had more joint disease (12.0 vs. 27.0%, p=0.013), more stroke history (5.6 vs. 17.5%, p=0.012) and higher incident of family history of cardiovascular disease (28.7 vs. 46.0%, p=0.025), but less religion (54.6 vs. 36.5%, p=0.002) and private health insurance (43.5 vs. 20.6%, p=0.002). The mean difference of BDI-II score between the baseline and pre-discharge was higher in patients with PCI (OR: 1.266; 95% CI: 1.146-1.398, p<0.001).ConclusionIn conclusion, PCI contributes independently to higher risk of developing depressive symptoms in CSA patients during hospitalization; Routine assessment and management of PCI related depressive symptoms are justified.

Influence of Cognitive Behavioral Therapy on Mood and Quality of Life After Stent Implantation in Young and Middle-Aged Patients With Coronary Heart Disease

“…2-4) Authors agree that many patients with CHD have persistent symptoms of depression and anxiety, 5,6) which significantly influence their quality of life (QOL) and prognosis, often leading to a vicious cycle. 7) However, whether the presence of depressive symptoms is due to depression after CHD or originates from the CHD itself is controversial.…”

“…(Int Heart J 2016; 57: 167-172) Key words: Cognitive behavioral therapy, Percutaneous stent implantation, Anxiety, Depression C oronary heart disease (CHD) is one of the leading causes of death worldwide. The China Cardiovascular Disease report published in 2010 stated that the incidence of CHD in China continues to increase, and that the age at onset is decreasing.1) The relationship between CHD and a change toward a negative mental status has attracted more and more attention, particularly the clinical studies of therapeutic intervention with regards to psychological and social factors of CHD.2-4) Authors agree that many patients with CHD have persistent symptoms of depression and anxiety, 5,6) which significantly influence their quality of life (QOL) and prognosis, often leading to a vicious cycle. 7) However, whether the presence of depressive symptoms is due to depression after CHD or originates from the CHD itself is controversial.…”

“…1) The relationship between CHD and a change toward a negative mental status has attracted more and more attention, particularly the clinical studies of therapeutic intervention with regards to psychological and social factors of CHD. [2][3][4] Authors agree that many patients with CHD have persistent symptoms of depression and anxiety, 5,6) which significantly influence their quality of life (QOL) and prognosis, often leading to a vicious cycle. 7) However, whether the presence of depressive symptoms is due to depression after CHD or originates from the CHD itself is controversial.…”

Association of depression with adverse cardiovascular events after percutaneous coronary intervention

“…The physical trauma and potential risks related to the procedure always lead to varieties of mental stress to patients. A bidirectional relationship between depression and revascularization has been reported by some studies [11][12][13]. The PCI procedure was found to contribute to a higher risk of new-onset depression in chronic stable angina patients during hospitalization [11].…”

“…A bidirectional relationship between depression and revascularization has been reported by some studies [11][12][13]. The PCI procedure was found to contribute to a higher risk of new-onset depression in chronic stable angina patients during hospitalization [11]. In contrast, the presence of depressive symptoms was associated with a poorer quality of life even after successful PCI [12].…”