Effects of pacing location on coronary circulation in dogs.

Miyazawa, Keiji; Shirato, Kunio; Haneda, Takashi; Honna, Takao; Arai, Toru; Nakajima, Toshiyuki

doi:10.1620/tjem.121.149

Tohoku J. Exp. Med.

1977

DOI: 10.1620/tjem.121.149

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Effects of pacing location on coronary circulation in dogs.

Keiji Miyazawa

Kunio Shirato

Takashi Haneda

et al.

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1978

1984

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Cited by 2 publications

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“…Our previous studies (Miyazawa et al 1976(Miyazawa et al , 1977a showed that ventricular pacing from various sites caused a diminution of cardiac output and systemic bood pressure as compared with right atrial pacing, and there were no significant differences in these hemodynamic parameters by changing the site of ventricular pacing. However, little information is available concerning the influence of asynchronous activation on the contraction patterns of the left ventricle and the relation with the cardiac pumping action (Ueda et al 1968;Herman and Gorlin 1969;Eber et al 1974).…”

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confidence: 97%

Dynamic Geometry of the Left Ventricle during Ventricular Pacing: Correlation with Cardiac Pumping Action

Miyazawa

Honna

Haneda

et al. 1978

Tohoku J. Exp. Med.

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-In five anesthetized open chest dogs, contraction patterns of the left ventricle induced by ventricular pacing were analyzed using cineangiocardiography.Left ventriculography was performed with dogs in the right anterior oblique position. The right atrial appendage (RA) and two ventricular sites (RVO: outflow tract of the right ventricle and LVA: apex of the left ventricle) were stimulated electri cally at a rate of 150 per min. Contraction patterns and cardiodynamics in response to ventricular pacing were compared with those to RA pacing, which represents a normal sequence and extent of ventricular contraction.RVO pacing resulted in asyneresis of anterior wall and normal contraction of posterior wall, while LVA pacing produced a systolic expansion of the apex associated with enhanced contraction of the posterior wall. Ventricular pacing uniformly caused decreases in left ventricular end-diastolic volume (LVEDV), stroke volume (SV) and ejection fraction (EF), with relatively constant left ventricular end-systolic volume (LVESV). Blood pressure was significantly decreased with ventricular pacing. There were only minor differences of these parameters between RVO and LVA pacing.It was considered that a diminution of SV and EF during ventricular pacing resulted from the asynchronous contraction of the ventricle which was not related to decreased myocardial contractility. cineangiocar diography; ventricular pacing; ventricular asynchrony; cardiac performance; pacemaker siteIt has been well known that ectopic ventricular beats are associated with asynchronous contraction of the left ventricle (Herman et al. 1967). Our previous studies (Miyazawa et al. 1976(Miyazawa et al. , 1977a showed that ventricular pacing from various sites caused a diminution of cardiac output and systemic bood pressure as compared with right atrial pacing, and there were no significant differences in these hemodynamic parameters by changing the site of ventricular pacing. However, little information is available concerning the influence of asynchronous activation on the contraction patterns of the left ventricle and the relation with the cardiac pumping action (Ueda et al. 1968;Herman and Gorlin 1969;Eber et al. 1974). In this regard, the present study was undertaken to describe the

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confidence: 97%

Dynamic Geometry of the Left Ventricle during Ventricular Pacing: Correlation with Cardiac Pumping Action

Miyazawa

Honna

Haneda

et al. 1978

Tohoku J. Exp. Med.

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Effect of pacemaker sites on contractile forces of the local myocardium and blood flow in the major branches of the left coronary artery in anesthetized open-chest dogs.

Saito¹,

Takeda²,

Hyodo³

et al. 1984

Jpn Circ J

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Effects of pacing location on coronary circulation in dogs.

Cited by 2 publications

References 11 publications

Dynamic Geometry of the Left Ventricle during Ventricular Pacing: Correlation with Cardiac Pumping Action

Dynamic Geometry of the Left Ventricle during Ventricular Pacing: Correlation with Cardiac Pumping Action

Effect of pacemaker sites on contractile forces of the local myocardium and blood flow in the major branches of the left coronary artery in anesthetized open-chest dogs.

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