Effects of oxidized vanaspati ghee on the serum lipids profile and radical scavenging activity of the in vitro lipids of liver, brain and muscles

Zeb, Alam; Mehmood, Arif

doi:10.5505/tjb.2012.63325

Cited by 12 publications

(16 citation statements)

References 16 publications

(20 reference statements)

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“…The peroxide values of the vanaspati ghee increase significantly after oxidation, and subsequently reduce the RSA values. The present result is in agreement with Zeb and Mehmood (2012) who reported an increase in the peroxide value of vanaspati ghee with increasing time of oxidation. The secondary oxidation products were measured in terms of anisidine value, which was increased significantly with oxidation compared to the control in vanaspati ghee.…”

Section: Groupsupporting

confidence: 96%

“…The results are in agreement with the finding of SBT oil against CCl 4 induced hepatotoxicity in rats (Hsu et al, 2009). Recent results by Zeb and Mehmood (2012) showed a dose dependent increase in triglycerides, total cholesterol and LDLcholesterol, while a statistically non-significant increase in the HDL-cholesterol of the rabbits. Similarly Shila et al (2011) observed that the serum total cholesterol, HDL-cholesterol and malondialdehyde increased significantly (p < 0.05) by feeding the oxidized oil as compared to fresh oil fed group.…”

Section: Groupsupporting

confidence: 94%

“…Lipids were extracted using the modified procedure of Folch, Lees, and Sloane-Stanley (1957). The radical scavenging assays (RSA) of the lipids extracted from the tissues were measured using DPPH free radicals (Zeb & Mehmood, 2012).…”

Section: Rsa Of Liver Lipidsmentioning

confidence: 99%

“…hepato-carcinoma in experimental animals (Jurek et al, 2005). Recently we have shown that thermally oxidized vanaspati ghee had produced significant effects in the serum lipid profile as well as peroxidation in different tissue (Zeb & Mehmood, 2012). It is therefore necessary to find out the possible remedies to counterbalance the oxidative stress produced by oxidized lipids in our daily foods.…”

Section: Introductionmentioning

confidence: 98%

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Sea buckthorn seed oil protects against the oxidative stress produced by thermally oxidized lipids

Zeb

Ullah

2015

Food Chemistry

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Section: Groupsupporting

confidence: 96%

Section: Groupsupporting

confidence: 94%

Section: Rsa Of Liver Lipidsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

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Sea buckthorn seed oil protects against the oxidative stress produced by thermally oxidized lipids

Zeb

Ullah

2015

Food Chemistry

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“…). High intakes of diets containing lipid per‐oxidation components may be associated with the generation of free radicals and thus causes oxidative stress (Zeb and Mehmood ).…”

Section: Introductionmentioning

confidence: 99%

Sea Buckthorn Seed Powder Provides Protection in the Oxidative Stress Produced by Thermally Oxidized Sunflower Oil in Rabbits

Zeb

Hussain

2014

Journal of Food Biochemistry

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SBT seed powder was used against the oxidative stress produced by thermally oxidized sunflower oil. OSFO and SBT powder were orally administered to the rabbits. Blood biochemistry, hematology and liver pathology were investigated. The results show that OSFO produce changes in the blood biochemistry and hematology and alterations in the liver. However, the toxicity of OSFO was minimized when rabbits were fed with SBT seed powder. The SBT seed both in independent and in fortified forms significantly decreases the serum cholesterol, LDL‐c, ALT (alanine aminotransferase) and TG values, whereas it increases serum glucose and HDL‐c values. The seed powder normalizes all the hematological indices. Histopathological investigation of the liver reveals that OSFO intake causes severe adverse changes, whereas SBT seed powder was found to restore the normal condition. It was concluded that SBT seed powder has strong potential to reduce the toxicity of oxidized lipids in model animals. Practical Applications Thermally oxidized edible oils are one of the main concerns of the modern‐day food chemists and technologists. The ingestion of these oxidized lipids results into the toxic effects on human beings. This study clearly showed for the first time that SBT seed powder reduces the degenerative and toxic changes in the liver produced by thermally oxidized lipids. It has been found that SBT seed powder supplementation has protective effects against the toxicity of OSFO by increasing the antioxidant potential.

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Toxicity of Food Frying

2019

Food Frying

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Effects of oxidized vanaspati ghee on the serum lipids profile and radical scavenging activity of the in vitro lipids of liver, brain and muscles

Cited by 12 publications

References 16 publications

Sea buckthorn seed oil protects against the oxidative stress produced by thermally oxidized lipids

Sea buckthorn seed oil protects against the oxidative stress produced by thermally oxidized lipids

Sea Buckthorn Seed Powder Provides Protection in the Oxidative Stress Produced by Thermally Oxidized Sunflower Oil in Rabbits

Toxicity of Food Frying

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