Effects of oral zinc supplementation on zinc status and catch-up growth during the first 2 years of life in children with non-organic failure to thrive born preterm and at term

Cho, Jin Min; Kim, Ju Young; Yang, Hye Ran

doi:10.1016/j.pedneo.2018.06.006

Cited by 15 publications

(12 citation statements)

References 37 publications

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“…In our study, the anthropometric parameters of WAZ and HAZ did not show differences between the supplemented and control groups. Cho et al [29], when evaluating children who received 5 mg-Zn/day for six months, also did not observe differences in WAZ and HAZ when compared with the control group. It should be emphasized that the population of our study, although classified as having negative scores at T0, neither demonstrated a deficit in height or weight at the beginning of the study, nor indicated zinc deficiency.…”

Section: Discussionmentioning

confidence: 98%

“…Recently, zinc supplementation studies with concentrations ranging from 5 to 50 mg-Zn/day in different infant populations to assess the influence on growth and development have been conducted [26,27,28,29]. In a systematic review, Liu et al [30] described that zinc supplementation improves growth parameters with potentially stronger effects in children after two years of age.…”

Section: Discussionmentioning

confidence: 99%

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Bioelectrical Impedance Vector Analysis and Phase Angle on Different Oral Zinc Supplementation in Eutrophic Children: Randomized Triple-Blind Study

et al. 2019

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The parameters derived from bioelectrical impedance, phase angle (PA) and bioelectrical impedance vector analysis (BIVA) have been associated with cell membrane integrity and body cell mass. Zinc is a micronutrient that exerts important structural functions and acts in maintaining cellular functionality. To evaluate cell integrity and body cell mass, PA and BIVA were evaluated in children orally supplemented with zinc at different concentrations. Anthropometric, bioelectrical (resistance and reactance) and serum zinc variables were collected from two randomized, triple-blind, controlled clinical trials. Sampling was composed of 71 children consisting of three groups: a control group who received a placebo and two experimental groups who received oral supplementation of 5 or 10 mg-Zn/day for three months. The three groups presented increases (p < 0.001) in the linear height and weight. In the group supplemented with 10 mg-Zn/day, there was an increase in reactance values (p = 0.036) and PA (p = 0.002), in addition to vector displacement (p < 0.001) in relation to the confidence ellipses. An increase in serum zinc concentration was found (p < 0.001) in all three groups. Whit this, the supplementation with 10 mg-Zn/day promotes changes in the integrity of the cell membrane associated with the increase in the cellular mass of healthy children.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Bioelectrical Impedance Vector Analysis and Phase Angle on Different Oral Zinc Supplementation in Eutrophic Children: Randomized Triple-Blind Study

et al. 2019

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“…It was reported that growth hormone is highly regulated by nutrition ( 50 ) and some studies showed that micronutrient intake improves early growth particularly in preterm infants ( 51 , 52 ) . It has been suggested that supplementation with multiple micronutrients rather than a single nutrient is more effective for catch-up growth in preterm and term infants ( 53 ) . On the other hand, micronutrient deficiencies can alter growth ( 54 ) .…”

Section: Discussionmentioning

confidence: 99%

Ethiopia’s high childhood undernutrition explained: analysis of the prevalence and key correlates based on recent nationally representative data

Gebreegziabher

Regassa

2019

Public Health Nutr.

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ObjectiveTo examine the contribution of child, maternal and household factors in stunting, wasting and underweight among children under 5 years in Ethiopia.DesignQuantitative cross-sectional design based on nationally representative data.SettingUrban and rural areas of Ethiopia.ParticipantsYounger (0–24 months; n 4199) and older age groups (25–59 months; n 5497), giving a total of 9696 children.ResultsAmong the younger age group, 29 % were stunted, 14 % were wasted and 19 % were underweight; and among the older age group, the prevalence of stunting, wasting and underweight was 47, 8 and 28 %, respectively. Being female, intake of multiple micronutrients, household having a piped source of drinking-water, high maternal BMI, higher household wealth and higher maternal education were associated with decreased odds of at least one form of undernutrition in both groups. On the other hand, children who were anaemic, had low birth weight, drank from a bottle, and children of stunted or wasted or working mothers were more likely to be stunted, wasted or underweight in both groups (P<0·05). While most predictors and/or risk factors followed a similar pattern across the two age groups, child factors had higher leverage in the younger than the older group across the three forms of undernutrition.ConclusionsMultiple set of factors predicted childhood undernutrition in Ethiopia. The study underscores the importance of intervening in the first 1000 days through promoting maternal education, maternal–child health services, mother’s nutrition and improving intrahousehold food distribution.

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“…There is also evidence that zinc supplementation can reduce the risk of respiratory infection [287,288] and pneumonia [99,288] in the same population. Recent meta-analyses of both observational data and clinical trials have shown that zinc supplementation can increase weight, height, and weight-for-age z-score in term infants [288][289][290], and that supplementation has the largest impact when begun before two years of age [289]. However, the authors conclude that multiple micronutrient supplementation is still superior to zinc supplementation alone in this age group [290].…”

Section: Zincmentioning

confidence: 99%

Nutritional Gaps and Supplementation in the First 1000 Days

Beluska-Turkan

Korczak²,

Hartell

et al. 2019

Nutrients

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Optimized nutrition during the first 1000 days (from conception through the 2nd birthday) is critical for healthy development and a healthy life for the newborn. Pregnancy and the postpartum period are accompanied by physiological changes, increased energy needs, and changing requirements in the nutrients critical for optimal growth and development. Infants and toddlers also experience physiological changes and have specific nutritional needs. Food and nutrition experts can provide women of childbearing age with adequate dietary advice to optimize nutrition, as well as guidance on selecting appropriate dietary supplements. Considering the approaching 2020–2025 Dietary Guidelines for Americans (DGA) will be making specific recommendations for children, it is important to provide accurate scientific information to support health influencers in the field of nutrition. The purpose of this review is to summarize the nutrition and supplementation literature for the first 1000 days; to highlight nutritional and knowledge gaps; and to educate nutrition influencers to provide thoughtful guidance to mothers and families. Optimal nutrition during pregnancy through early childhood is critical for supporting a healthy life. Nutrition influencers, such as dietitians, obstetricians/gynecologists, and other relevant health professionals, should continue guiding supplement and food intake and work closely with expectant families and nutrition gatekeepers.

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Effects of oral zinc supplementation on zinc status and catch-up growth during the first 2 years of life in children with non-organic failure to thrive born preterm and at term

Cited by 15 publications

References 37 publications

Bioelectrical Impedance Vector Analysis and Phase Angle on Different Oral Zinc Supplementation in Eutrophic Children: Randomized Triple-Blind Study

Bioelectrical Impedance Vector Analysis and Phase Angle on Different Oral Zinc Supplementation in Eutrophic Children: Randomized Triple-Blind Study

Ethiopia’s high childhood undernutrition explained: analysis of the prevalence and key correlates based on recent nationally representative data

Nutritional Gaps and Supplementation in the First 1000 Days

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