Effects of oral vitamin E and β-carotene supplementation on ultraviolet radiation–induced oxidative stress in human skin

McArdle, Francis; Rhodes, Lesley; Parslew, Richard; Close, Graeme L.; Jack, Cia; Friedmann, Peter S.; Jackson, Malcolm J.

doi:10.1093/ajcn/80.5.1270

Cited by 84 publications

(58 citation statements)

References 36 publications

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“…Chow et al [17] reported that a 4-week intake of green tea polyphenols (800 mg/ day of epigallocatechin gallate) did not affect the MED of the subjects. Similarly, McArdle et al [18] found that supplementation with vitamin E or ␤ -carotene did not affect the skin's sensitivity to UV light.…”

Section: Discussionmentioning

confidence: 95%

Anti-Inflammatory and Skin-Hydrating Properties of a Dietary Supplement and Topical Formulations Containing Oligomeric Proanthocyanidins

Hughes-Formella¹,

Wunderlich²,

Williams³

2006

Skin Pharmacol Physiol

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Background: Anti-inflammatory and skin hydration properties of a dietary supplement and 2 topical formulations (Anthogenol®) with oligomeric proanthocyanidins were investigated. Methods: Forty-two subjects were randomized into 2 groups: one taking the dietary supplement (100 mg/day) and the other without supplement. After 4 weeks, erythema was induced using UV radiation followed by treatment with topical cream or lotion. Erythema was measured for up to 72 h after irradiation. Skin hydration after 1 and 2 weeks of application of the cream and lotion was also measured in separate test fields. Results: Both topical formulations led to a significant suppression of erythema formation and the dietary supplement led to an additional slightly stronger suppression. Thus 72 h after UV exposure and compared to the control fields of patients that had not taken a dietary supplement, erythema was slightly (13.2%) lower in the subjects that had taken a dietary supplement. The cream resulted in a maximal reduction of erythema of 45.9% (p = 0.0015), while the lotion resulted in a maximal reduction of 53.1% (p = 0.0002). Both topical formulations also increased skin hydration (by nearly 20%; p < 0.002 for all combinations of dietary supplementation and topical treatment) and the hydration was higher in the group taking the dietary supplement. Conclusion: The regular use of Anthogenol® products may help to protect from free-radical-mediated skin inflammation and to increase skin hydration.

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Section: Discussionmentioning

confidence: 95%

Anti-Inflammatory and Skin-Hydrating Properties of a Dietary Supplement and Topical Formulations Containing Oligomeric Proanthocyanidins

Hughes-Formella¹,

Wunderlich²,

Williams³

2006

Skin Pharmacol Physiol

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“…Derg. 40(1): [36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53]2016 Şen 39 fotohasarın şiddetiyle orantılıdır. Tip IV kollagen dermoepidermal bileşkedeki temel kollajen olup mekanik etkileşim için büyük önem taşımaktadır.…”

Section: Yaşlanma Sonucu Deride Görülen Değişikliklerunclassified

Deri yaşlanması ve antioksidanların önemi

Şen¹

2016

Ankara Üniversitesi Eczacılık Fakültesi Dergisi

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“…Also, there are a few papers that indicated the absence of a positive action of supplemented antioxidants on skin health [112,119,138,149,151] .…”

Section: Systemic Application Of Synthetic and Extracted Antioxidantsmentioning

confidence: 99%

Effect of Supplemented and Topically Applied Antioxidant Substances on Human Tissue

Darvin

Zastrow

Sterry

et al. 2006

Skin Pharmacol Physiol

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Systemic and topical application of antioxidant substances for the medical treatment and prophylaxis of many diseases as well as additional protection of the skin against the destructive action of free radicals and other reactive species has become very popular during the past years. Stimulated by the positive results of a fruit and vegetable diet in supporting medical treatment and in cosmetics, artificial and extracted antioxidant substances have been broadly applied. Surprisingly, not only positive but also strong negative results have been obtained by different authors. According to study reports artificial and extracted antioxidant substances support different kinds of medical therapies, if they are applied in mixtures of different compounds at low concentration levels. In the case of the application of high concentration of some single compounds, side effects were often observed. Regarding skin treatment by systemically applied antioxidant substances for cosmetic purposes, positive cosmetic effects as well as no effects, but almost no side effects, apart from a number of allergic reactions, were reported. One reason for this seems to be the lower concentration of systemically applied antioxidant substances in comparison with a medical application. Topical application of antioxidant substances is closely related to cosmetic treatment for skin protection and anti-aging. Positive results were also obtained in this case. The present review is an attempt to classify and summarize the published literature concerning the efficiency of action of systemic and topical applications of antioxidant substances, such as carotenoids and vitamins, on human organism and especially on the skin. The available literature on this topic is very extensive and the results are often contradictory. Nevertheless, there are some clear tendencies concerning systemic and topical application of antioxidant substances in medicine and cosmetics, and we summarize them in the present paper.

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Effects of oral vitamin E and β-carotene supplementation on ultraviolet radiation–induced oxidative stress in human skin

Cited by 84 publications

References 36 publications

Anti-Inflammatory and Skin-Hydrating Properties of a Dietary Supplement and Topical Formulations Containing Oligomeric Proanthocyanidins

Anti-Inflammatory and Skin-Hydrating Properties of a Dietary Supplement and Topical Formulations Containing Oligomeric Proanthocyanidins

Deri yaşlanması ve antioksidanların önemi

Effect of Supplemented and Topically Applied Antioxidant Substances on Human Tissue

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