Effects of oral administration of formaldehyde on albino rat stomach

Toxicological effect of formalin as food preservative on kidney and liver tissues in mice model

“…However, we did not observe any tumor in liver, kidney or any other organ. Some work of formalin through drinking water and food stuff on stomach and other tissue of mice, dogs and rat demonstrated little effect except for mild pharyngeal and gastric discomfort, significant increase in the thickness of the stomach lining epithelium [26]and irritation in mucus membrane, but such harmful effect was also alleviated' by diluting the formaldehyde prior to ingestion [27], [28].Inflammatory lesions in digestive system following oral administration formaldehyde has been reported in claves [29] and rats [30], [31], [32].The current observation showed that nature and intensity of histological alteration exposure through oral introduction of formalin are dose and time Toxicological effect of formalin as food preservative on kidney and liver tissues in mice model.…”