Effects of oppositely charged moieties on the self-assembly and biophysicochemical properties of polyurethane micelles

Abstract

Gemini quaternary ammonium (GQA), a type of cationic surfactant, exhibits superior performance to improve the micellization ability and acts as a cell internalization promoter to increase the permeability of the...

Effect of zwitterionic sulfobetaine incorporation on blood behaviours, phagocytosis, and in vivo biodistribution of pH-responsive micelles with positive charges

“…Once injected into the blood, polymeric micelles as nonspecific antigens usually cause a series of nonspecific immune reactions, such as immune cells phagocytosis. 44 The phagocytosis plays a major role in immune defense systems during clearing foreign molecules from the blood and often occurs before polymeric micelles target the lesion site. Only micelles evading phagocytosis can reach their destination and fulfill their task in the body.…”