Abstract:Aim: Hepatic ischemia-reperfusion (IR) injury is a major complication associated with liver transplantation and surgery. The aim of this study is to investigate the cytoprotective effects of nitrite on hepatic IR injury. Methods: Groups were arranged as follows: control, sham, IR protocol (45 minutes ischemia, 5 hours reperfusion) and study groups administered with 4 different concentrations of sodium nitrite given 12 and 24 hours prior to protocol. After IR protocol, serum transaminase and lactate dehydrogena… Show more
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