Two high-strength copper alloys, cold-worked-and-aged AHZIRC (Cu-Zr) and AMAX-MZC (Cu-Cr-Zr-Mg), were irradiated with 14-MeV Cu ions to a damage level of 10 dpa at temperatures of 100 to 500°C. Cross-section examination of the irradiated foils using electron microscopy revealed signs of irradiation-enhanced recrystallization for irradiation temperatures above 300°C. The recrystallization temperature for both alloys is about 450°C during thermal annealing for a time similar to the ionirradiation time -1.5 h. A simplified analysis of the results suggests that the accelerated recrystallization kinetics is due to radiationenhanced diffusion (RED). This process may restrict the maximum operating temperature of fusion reactor components that incorporate these types of alloys to temperatures as low as 200°C.