Effects of negative emotion and its correlated neural activity on secretory immunoglobulin A

Li, Fan; Bu-Xin, Han; Ren, Jun; Luo, Jing

doi:10.1007/s11434-008-0233-5

Cited by 4 publications

(6 citation statements)

References 46 publications

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“…Prediction b) was consistent with experimental observations that linked cognitive reappraisal with better immune function during stress: our previous study found that participants with higher PCSs and the intrinsic tendency to use cognitive reappraisal in processing unpleasant pictures demonstrated an immediate SIgA increase in stress [20] . Koh et al found that the personality characteristic of positive reappraisal assessed by a questionnaire was linked with improved immune function [33] .…”

Section: Introductionsupporting

confidence: 89%

“…Such pictures are widely used in studies on emotion and negative emotion. In order to control for individual difference in intrinsic tendency to use cognitive reappraisal strategies [20] , [21] and therefore successfully produce consistent inhibitory effects on SIgA immunity, we selected people with low positive coping scores (PCSs) as participants, who did not show a tendency to use cognitive reappraisal strategies when faced with stressful situations until the experimenter taught them to do so. This enables us to obtain a consistent inhibitory effect of negative emotional arousal on SIgA immunity and to further examine whether cognitive reappraisal regulation reverses this tendency.…”

Section: Introductionmentioning

confidence: 99%

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The Integrative Effects of Cognitive Reappraisal on Negative Affect: Associated Changes in Secretory Immunoglobulin A, Unpleasantness and ERP Activity

Zhang

Qin

et al. 2012

PLoS ONE

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Although the regulatory role of cognitive reappraisal in negative emotional responses is widely recognized, this reappraisal's effect on acute saliva secretory immunoglobulin A (SIgA), as well as the relationships among affective, immunological, and event-related potential (ERP) changes, remains unclear. In this study, we selected only people with low positive coping scores (PCSs) as measured by the Trait Coping Style Questionnaire to avoid confounding by intrinsic coping styles. First, we found that the acute stress of viewing unpleasant pictures consistently decreased SIgA concentration and secretion rate, increased perceptions of unpleasantness and amplitude of late positive potentials (LPPs) between 200–300 ms and 400–1000 ms. After participants used cognitive reappraisal, their SIgA concentration and secretion rate significantly increased and their unpleasantness and LPP amplitudes significantly decreased compared with a control condition. Second, we found a significantly positive correlation between the increases in SIgA and the decreases in unpleasantness and a significantly negative correlation between the increases in SIgA and the increases in LPP across the two groups. This study is the first to demonstrate that cognitive reappraisal reverses the decrease of SIgA. In addition, it revealed strong correlations among affective, SIgA and electrophysiological changes with convergent multilevel evidence.

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Section: Introductionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

The Integrative Effects of Cognitive Reappraisal on Negative Affect: Associated Changes in Secretory Immunoglobulin A, Unpleasantness and ERP Activity

Zhang

Qin

et al. 2012

PLoS ONE

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“…Posterior P3 (or LPP), as an index of an inhibi-tion of task-irrelevant information, has demonstrated that it also represents later conscious categorization, decisionmaking and premotor response-related activities [27,28]. Li et al [31] reported extremely negative pictures elicited smaller LPPs than less negative pictures in the evaluation stage of emotion processing, which did not follow the negativity bias. In Yuan et al's experiment [30], a smaller LPP was elicited by negative stimuli rather than by positive and neutral stimuli which reflected the degree to which individuals inhibit the task-irrelevant information.…”

Section: Discussionmentioning

confidence: 99%

Attentional negativity bias moderated by positive mood arousal

Chen

Luo

2010

Chin. Sci. Bull.

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That individuals focus on emotionally negative events more than to neutral or positive events, which is designated as emotional negativity bias, has been demonstrated by many behavioral studies. For example, snakes and spiders were detected more rapidly than flowers and mushrooms in a visual search task, suggesting that threat-relevant stimuli in the environment are preferentially perceived [1]. Researchers assumed this privileged access to negative stimulation may be driven by the pre-attentive analysis of stimuli as being threat-related (e.g., snakes, spiders), and that the underlying mechanism may consequently lead to an automatic shift of attention resources to the location of the threatening object [2,3]. Similarly, the attention bias towards negative stimuli is reflected by impaired reaction time (RT) in an emotional Stroop task which requires participants to name the color ink of words varying in emotional value (e.g., neutral versus threat-related words), wherein the RTs between word types are compared [4]. Typically, the longer the RTs, the more psychological resources are put into the processing of negative information. Because participants are presumably distracted by the nature of the words, the RTs of the color-naming task are correspondingly prolonged.RT studies establish the presence of an attention bias. ERPs provided a better examination than RTs of the time course to information processing during sensory and cognitive stages [5]. Negativity bias in earlier ERP components has also been documented by some literature. One of ERP's components, the P2 which appeared approximately at 200 -250 ms poststimulus onset, would be a good index to mirror attention bias. Thomas et al. [6] reported that the amplitude of P2 was specific to stimulus valence and larger P2 amplitudes were required for threat words than for neutral words. Likewise, Huang and Luo [7] found that enlarged P2 amplitudes are solely observed for negative rather than for positive and neutral stimuli. Carretie et al.[8] explored the ERPs for positive, negative and neutral pictorial stimuli in normal participants. They found that the P2 post-target component had the highest amplitudes for negative stimuli. It remains uncertain whether or not enhanced P2 verifies negative stimuli receive more attention than positive stimuli. Chen et al. [9] reported participants who experienced either positive or negative moods elicited smaller P2 amplitudes from negative pictures compared to positive pictures. A smaller P2 elicited by negative but not neutral stimuli was also observed in anxious and female participants [10,11]. Another possible candidate for this effect is the late positive

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“…Therefore, it was hypothesized that sexual experience would elevate levels of CREB in the NAcSh, and this manipulation could counteract decreased CREB activity induced by social isolation. CREB is expressed throughout the brain and it is crucial in the regulation of individual emotionality-a type of subjective experience [52] within a specific neural circuit [48]. That is, behavioral adaptations would be observed at times, which could explain the comparable anxiety-and depressive-like behaviors in rats isolated for 7 d. Evidence suggests that CREB function in the NAcSh regulates anxiety-like behavior [10,38,48,53], while it is important to mediate depressive-like behavior via CREB in the hippocampus [48].…”

Section: Discussionmentioning

confidence: 99%

Effects of isolation after sexual experience on anxiety-like, depressive-like behaviors and affective states in male rats

Wen

2010

Chin. Sci. Bull.

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Studies on social isolation have provided evidence for an enhanced anxiety-like phenotype, depressive-like symptoms and higher levels of 22-kHz ultrasonic vocalizations (USVs); whereas sexual experience could induce significant changes in affective states, decrease anxiety-and depressive-like responses. However, the behavioral and emotional alterations in male rats exposed to isolation after sexual experience remain poorly understood. Therefore, the present study examined anxiety-and depressive-like parameters, as well as USV emissions in male rats isolated for 1, 2, or 7 d following 1-week sexual (male-female paired housing) or social (male-male paired housing) interaction. Isolation for 1 d resulted in increased depressive-like symptoms, and 2-d isolation induced elevated anxiety-like behavior in sexually inexperienced rats, while rats with sexual experience exhibited comparable levels of emotionality at each isolation time. Moreover, isolated rats without sexual experience emitted less 22-and 50-kHz USVs, but sexually experienced rats exhibited similar affective states compared with control ones. These results suggested that prior sexual experience could have a modulatory effect on experimental rat emotional responses to isolation. social isolation, sexual experience, anxiety-like, depressive-like, ultrasonic vocalization (USV) Citation:Wen F, Xu L. Effects of isolation after sexual experience on anxiety-like, depressive-like behaviors and affective states in male rats.

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Effects of negative emotion and its correlated neural activity on secretory immunoglobulin A

Cited by 4 publications

References 46 publications

The Integrative Effects of Cognitive Reappraisal on Negative Affect: Associated Changes in Secretory Immunoglobulin A, Unpleasantness and ERP Activity

The Integrative Effects of Cognitive Reappraisal on Negative Affect: Associated Changes in Secretory Immunoglobulin A, Unpleasantness and ERP Activity

Attentional negativity bias moderated by positive mood arousal

Effects of isolation after sexual experience on anxiety-like, depressive-like behaviors and affective states in male rats

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