Effects of nanoplastics on Mytilus galloprovincialis after individual and combined exposure with carbamazepine

Brandts, I.; Teles, Mariana; Gonçalves, A. Pedro; Barreto, Ângela; Franco‐Martínez, Lorena; Martins, Manuel A.; Soares, Amadeu M.V.M.; Tort, L.; Oliveira, Miguel

doi:10.1016/j.scitotenv.2018.06.257

Cited by 290 publications

(97 citation statements)

References 60 publications

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“…Microplastics or nanoplastics inhibit the efflux pump and induce cytotoxicity in human intestinal cells [112]. The cytotoxicity induced by microplastics and/or nanoplastics stimulates oxidative stress via free radical generation originating from reactive oxygen species (ROS) [98,101,103,[113][114][115]. Several studies have shown this connection in monogonont rotifer [116], Caenorhabditis elegans [117], Danio rerio [118], mouse liver [119], and human intestine cell lines [112].…”

Section: Molecular and Cellular Mechanisms Of Plastic Micromaterials Amentioning

confidence: 99%

“…PS microplastics also increased the acetylcholinesterase (AChE) activity and the related neurotransmitters such as threonine, aspartate, and taurine in a mouse model [122]. In addition, microplastics and nanoplastics elicit immunological responses [115,123,124], alter gene expression [88,103,113,114,125] and induce genotoxicity [113,126]. In kidney cells, VC stimulates the expression of fibrosis-related proteins, such as CTGF, PAI-1, and collagen 1, and autophagy-related proteins, such as Beclin 1 and LC3-II [127].…”

Section: Molecular and Cellular Mechanisms Of Plastic Micromaterials Amentioning

confidence: 99%

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Potent Impact of Plastic Nanomaterials and Micromaterials on the Food Chain and Human Health

Wang

Lee

Chiu

et al. 2020

IJMS

107

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Plastic products are inexpensive, convenient, and are have many applications in daily life. We overuse plastic-related products and ineffectively recycle plastic that is difficult to degrade. Plastic debris can be fragmented into smaller pieces by many physical and chemical processes. Plastic debris that is fragmented into microplastics or nanoplastics has unclear effects on organismal systems. Recently, this debris was shown to affect biota and to be gradually spreading through the food chain. In addition, studies have indicated that workers in plastic-related industries develop many kinds of cancer because of chronic exposure to high levels of airborne microplastics. Microplastics and nanoplastics are everywhere now, contaminating our water, air, and food chain. In this review, we introduce a classification of plastic polymers, define microplastics and nanoplastics, identify plastics that contaminate food, describe the damage and diseases caused by microplastics and nanoplastics, and the molecular and cellular mechanisms of this damage and disease as well as solutions for their amelioration. Thus, we expect to contribute to the understanding of the effects of microplastics and nanoplastics on cellular and molecular mechanisms and the ways that the uptake of microplastics and nanoplastics are potentially dangerous to our biota. After understanding the issues, we can focus on how to handle the problems caused by plastic overuse.

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Section: Molecular and Cellular Mechanisms Of Plastic Micromaterials Amentioning

confidence: 99%

Section: Molecular and Cellular Mechanisms Of Plastic Micromaterials Amentioning

confidence: 99%

Potent Impact of Plastic Nanomaterials and Micromaterials on the Food Chain and Human Health

Wang

Lee

Chiu

et al. 2020

IJMS

107

View full text Add to dashboard Cite

show abstract

“…They have been able to induce decreases in zooplankton feeding rates and reproduction [20], concentrate environmental pollutants [21], modify the distribution, biotransformation and effects of other environmental contaminants (e.g. PAHs and pharmaceuticals) upon simultaneous exposure [22,23]. They have been reported to induce genotoxicity and neurotoxicity in fish and mussels [22,23], promote alterations of behavior [24] and cause endocrine disruption [25] in fish.…”

Section: Plastics In the Environment: Sources And Environmental Impactmentioning

confidence: 99%

“…PAHs and pharmaceuticals) upon simultaneous exposure [22,23]. They have been reported to induce genotoxicity and neurotoxicity in fish and mussels [22,23], promote alterations of behavior [24] and cause endocrine disruption [25] in fish. Laboratory studies suggest that microplastic particles may be passed up the food web [26] and thus, also potentially be a vector for the transfer of environmental contaminants.…”

Section: Plastics In the Environment: Sources And Environmental Impactmentioning

confidence: 99%

“…However, this subject is understudied [2,12] and available data is scarce. The reported toxic effects of micro(nano)plastics in aquatic species such as immunomodulation and apoptosis [38], generation of reactive oxygen species and peroxidative damage [23], impaired neurotransmission [22], translocation of micro(nano)plastics from the digestive track to the circulatory system and internal organs [36], brain and liver and continuous inflammatory activation suggest that these particles may also be toxic to humans (Table SI 1). However, no studies are available in terms of effects of micro(nano)plastics of environmental origin on humans.…”

Section: Plastics and Human Health: Potential Sources And Effects On mentioning

confidence: 99%

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A micro(nano)plastic boomerang tale: A never ending story?

Oliveira

Almeida

Miguel

2019

TrAC Trends in Analytical Chemistry

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Plastics are an integral but largely inconspicuous part of human daily routines. Associated with a high production and single use nature of several products, small plastic particles became ubiquitous. Due to processes like water currents and winds, plastics may occur far from their place of origin and affect biota at different environmental compartments. In the environment plastics can degrade into increasingly smaller particles, reaching a nanometer size which increases their potential to be incorporated by organisms. Currently it is recognized that the plastics in the environment are reaching humans via contaminated food, drinks, and air but their effects on humans are largely unknown. In this paper, the potential exposure routes and effects to humans are discussed and approaches to decrease impact of microplastics to humans presented.

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Microplastic Toxicity to Humans

Madeła

2023

Microplastics in the Ecosphere

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Effects of nanoplastics on Mytilus galloprovincialis after individual and combined exposure with carbamazepine

Cited by 290 publications

References 60 publications

Potent Impact of Plastic Nanomaterials and Micromaterials on the Food Chain and Human Health

Potent Impact of Plastic Nanomaterials and Micromaterials on the Food Chain and Human Health

A micro(nano)plastic boomerang tale: A never ending story?

Microplastic Toxicity to Humans

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