Effects of Naltrexone on Repressive Coping and Disclosure of Emotional Material: A Test of the Opioid-Peptide Hypothesis of Repression and Hypertension

Younger, Jarred; Lawler-Row, Kathleen A.; Moe, Krista; Kratz, Anna L.; Keenum, Amy J.

doi:10.1097/01.psy.0000234029.38245.c9

Cited by 12 publications

(4 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Opioid antagonism reduced repression. These results suggest that endogenous opioid dysregulation may underlie repressive coping (Younger, Lawler-Roe, Moe, Kratz, & Keenan, 2006). However, this should be seen as a preliminary study due to the low number of participants and more detailed research is required.…”

Section: Physiological Mechanisms Underlying Repressive Copingmentioning

confidence: 67%

The importance of the repressive coping style: findings from 30 years of research

Myers

2010

Anxiety, Stress & Coping

View full text Add to dashboard Cite

During the last three decades there has been substantial research exploring the repressive coping style as defined by Weinberger, Schwartz, and Davidson. As "repressors," who score low on trait anxiety and high on defensiveness, account for up to 50% of certain populations, they are an essential group for psychologists to study. However, there are methodological issues in identifying repressors as well as considerable evidence that repressors avoid negative self-relevant information. Possible methods of addressing these difficulties are discussed in this review. Importantly, there is a body of evidence linking repressive coping and poor physical health, including heart disease and cancer. However, some preliminary findings suggest that repressors compared to non-repressors may be better at health behaviors that they perceive as under their personal control. This needs more extensive investigation as such behaviors are only one aspect of health and other factors may contribute to repressors' poor physical health. Possible future directions of research are discussed including: the need for systematic empirical research of a new theory of repressive coping--the Vigilance-Avoidance Theory--more longitudinal health studies, and an in-depth exploration of the physiological mechanisms which may underlie repressive coping.

show abstract

Section: Physiological Mechanisms Underlying Repressive Copingmentioning

confidence: 67%

The importance of the repressive coping style: findings from 30 years of research

Myers

2010

Anxiety, Stress & Coping

View full text Add to dashboard Cite

show abstract

“…It is interesting that the effects of naltrexone may be observed so long after administration. The delayed effect of naltrexone has been previously reported [49], and may be due to the extended half-life of the 6-β-naltrexol metabolite [50], [51]. It is unknown if naltrexone would have produced changes in pain processing if measured at a later time-point.…”

Section: Discussionmentioning

confidence: 96%

Effects of Naltrexone on Pain Sensitivity and Mood in Fibromyalgia: No Evidence for Endogenous Opioid Pathophysiology

2009

Self Cite

View full text Add to dashboard Cite

The pathophysiological mechanisms underlying fibromyalgia are still unknown, although some evidence points to endogenous opioid dysfunction. We examined how endogenous opioid antagonism affects pain and mood for women with and without fibromyalgia. Ten women with fibromyalgia and ten age- and gender-matched, healthy controls each attended two laboratory sessions. Each participant received naltrexone (50mg) at one session, and placebo at the other session, in a randomized and double-blind fashion. Participants were tested for changes in sensitivity to heat, cold, and mechanical pain. Additionally, we collected measures of mood and opioid withdrawal symptoms during the laboratory sessions and at home the night following each session. At baseline, the fibromyalgia group exhibited more somatic complaints, greater sensory sensitivity, more opioid withdrawal somatic symptoms, and lower mechanical and cold pain-tolerance than did the healthy control group. Neither group experienced changes in pain sensitivity due to naltrexone administration. Naltrexone did not differentially affect self-reported withdrawal symptoms, or mood, in the fibromyalgia and control groups. Consistent with prior research, there was no evidence found for abnormal endogenous opioid activity in women with fibromyalgia.

show abstract

“…People with high neuroticism displayed a graded cortisol, but not ACTH response to naloxone, whereas those with low neuroticism displayed a cortisol response that plateau (718). Reductions by naltrexone were observed on repressive coping and disclosure of emotional material (1278). Volunteers displayed less alertness, increased sedation and increased effort to perform a driving test following oxycodone/paracetamol relative to the NSAID, bromfenac (1157).…”

Section: B Moodmentioning

confidence: 99%

Endogenous opiates and behavior: 2009

Bodnar

2010

Peptides

View full text Add to dashboard Cite

Effects of Naltrexone on Repressive Coping and Disclosure of Emotional Material: A Test of the Opioid-Peptide Hypothesis of Repression and Hypertension

Abstract: The results support the hypothesis that endogenous opioid dysregulation underlies both hypertension and repressive phenomena.

Cited by 12 publications

References 74 publications

The importance of the repressive coping style: findings from 30 years of research

The importance of the repressive coping style: findings from 30 years of research

Effects of Naltrexone on Pain Sensitivity and Mood in Fibromyalgia: No Evidence for Endogenous Opioid Pathophysiology

Endogenous opiates and behavior: 2009

Contact Info

Product

Resources

About