Effects of Nalbuphine Combined with Anterior Serratus Plane Block in Elderly Patients Undergoing Thoracoscopic Surgery

Abstract

Postoperative pain in elderly patients with lung cancer after thoracoscopic surgery is still an important factor affecting the prognosis of patients. In this study, 200 elderly patients with lung cancer who were positive and planned to undergo video-assisted thoracoscopic surgery were randomly divided into four groups: control group, SAPB (serratus anterior plane block) group, Nalbuphine group and Nalbuphine + SAPB group. The effects of drugs and nerve block on the perioperative indexes of elderly patients were observed. The results showed that ① The VAS and SAS scores of postoperative analgesia in the Nalbuphine + SAPB group were lower than those in the single group and the control group. ② The postoperative spontaneous respiratory recovery time, extubation time, resuscitation room stay time, extubation cough, restlessness and respiratory depression in the Nalbuphine + SAPB group were lower than those in the single group and the control group. ③ The heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and blood oxygen saturation (SpO2) of patients in Nalbuphine + SAPB group before induction, T2 after intubation, T3 before skin incision, T4 after skin incision, T5 after chest closure and T6 after extubation were lower than those in single group and control group. Therefore, this study concluded that Nabufine combined with SAPB can make the vital signs of intraoperative patients more stable, which is worthy of clinical promotion.

Analysis of Research Trends in Traditional Chinese Medicine Treatments for Pes Anserine Bursitis from 2014 to 2024: Using the Search Results of China National Knowledge Infrastructure

“…NSAIDs는 심혈관 혈전증, 위장 부작용, 간 및 신장 기능 손상의 위험이 있으며 스테로이드 주사는 피 하 조직 위축, 피부 색소 침착, 힘줄 파열과 같은 합병 증을 유발한다고 알려져 있어 5) 대안적 치료법이 필요 한 상황이다. 거위발 점액낭염은 한의학에서 "痹症", "筋傷"의 범 주로 다루며 반복적인 스트레스, 外傷, 風寒濕邪 등의 외부요인으로 인해 氣滯瘀血하여 경락의 운행이 막히 고 不通則痛하여 발생하여 活血化瘀, 舒筋通络 해야 한 다고 보았다 7) . 또한 ≪靈樞, 終始≫ "在筋守筋" 8) , ≪素 問, 痿論≫ "宗筋主束骨而利機關也" [7][8][9][11][12][13][14][15][16][17][18][19][20][21] , 증례보고 3편 [22][23][24] , 총 17편의 논문을 선정하였다(Fig.…”