Effects of Multiple Sclerosis on Female Sexuality: A Controlled Study

Gümüş, Haluk; Akpınar, Zehra; Yılmaz, Halim

doi:10.1111/jsm.12397

Cited by 54 publications

(62 citation statements)

References 38 publications

(55 reference statements)

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“…Finally, sexual dysfunction may results from psychological factors as well. Sexual dysfunction was positively correlated with depression in several studies (Gumus et al, 2014;Lew-Starowicz and Rola, 2014). Given the great impact of sexual dysfunction in the social life of MS patients, this association is not surprising.…”

Section: Sexual Dysfunctionmentioning

confidence: 77%

“…The existence of any impact of relapses on sexual dysfunction is still debated, since conflicting results were obtained by different authors (Mattson et al, 1995;Zorzon et al, 2001). Other authors also found that sexual dysfunction correlates positively with bladder dysfunction (Gumus et al, 2014;Lew-Starowicz and Rola, 2014). Finally, sexual dysfunction may results from psychological factors as well.…”

Section: Sexual Dysfunctionmentioning

confidence: 86%

See 1 more Smart Citation

Autonomic dysfunction in multiple sclerosis

Racosta

Kimpinski

Morrow

et al. 2015

Autonomic Neuroscience

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Section: Sexual Dysfunctionmentioning

confidence: 77%

Section: Sexual Dysfunctionmentioning

confidence: 86%

Autonomic dysfunction in multiple sclerosis

Racosta

Kimpinski

Morrow

et al. 2015

Autonomic Neuroscience

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“…Gumus et al. have found negative correlations for Female Sexual Function Index (FSFI) score with Beck Depression Inventory (BDI) score, Expanded Disability Status Scale (EDSS) score, pain, age, and disease duration, as well as a positive correlation with the level of education, in a sample of 70 MS women [12]. The negative correlation of BDI score with SF was confirmed by Mohammadi et al.…”

Section: Introductionmentioning

confidence: 82%

Correlates of Sexual Function in Male and Female Patients with Multiple Sclerosis

Lew–Starowicz

Rola

2014

The Journal of Sexual Medicine

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Introduction Many factors have been suggested to contribute to sexual dysfunction (SD) in multiple sclerosis (MS) patients, but the research on their impact on sexual functioning (SF) and sexual quality of life (SQoL) remains scant. Aim The aim of this study was to investigate correlates of SF and SQoL in MS patients, as well as possible gender differences. Methods 204 MS patients were interviewed, completed the questionnaires, and underwent neurological assessment. Main Outcome Measure Primary outcome measures included the International Index of Erectile Function, the Female Sexual Function Questionnaire, the Sexual Quality of Life Questionnaire, the Beck Depression Inventory, and the Expanded Disability Status Scale. Results The course and duration of the disease did not predict patients' SF. Negative correlations were found for brainstem symptoms with orgasmic function and overall satisfaction in men and between cognitive functioning and the partner domain in women. Interestingly, brainstem symptoms correlated positively with the arousal domain in women. More than half (52.1%) of patients fulfilled Beck Depression Inventory criteria for depression, and these patients showed more SD than nondepressive individuals. The strongest negative correlations with depressive symptoms were found for desire, erectile function, and overall satisfaction with sexual life in men and for orgasm and sexual enjoyment in women. Deterioration in particular domains of SF was clearly related with diminished SQoL. The main gender difference was a strong influence of decreased desire on SQoL in women and no such correlation in men. Negative assessment of the relationship with partner significantly affected all domains of SF and SQoL in MS women and the desire domain in MS men. Conclusions Several correlates of SF in MS patients were found. The role of brainstem symptoms needs further investigation. Clinicians should pay close attention to depressive symptoms and relationship factors in MS patients who suffer from SD.

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“…In 2006, a survey of 4,267 patients with MS living in the United States found that perception of body image worsened if the patient was less educated, female, had a longer disease duration, and a greater degree of disability [4]. Another study found that the number of sexual encounters per week was lower in women with MS compared to the general population [5]. These findings suggest that predictors of sexual dysfunction in women with MS are diverse and multifactorial.…”

Section: Effect Of Ms On Pregnancy Sexual Dysfunctionmentioning

confidence: 94%

“…Several studies have informed our current understanding of the influencing factors and consequences of sexual dysfunction in women living with MS [1][2][3][4][5]. In 2006, a survey of 4,267 patients with MS living in the United States found that perception of body image worsened if the patient was less educated, female, had a longer disease duration, and a greater degree of disability [4].…”

Section: Effect Of Ms On Pregnancy Sexual Dysfunctionmentioning

confidence: 99%

The Effects of Multiple Sclerosis and Disease Modifying Therapy on Pregnancy

Johal

2017

UOJM

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Multiple sclerosis (MS) is a common inflammatory disorder of the central nervous system (CNS) in which the myelin sheath is targeted and subsequently degraded. In MS, disease modifying therapies (DMT) aim to decrease the relapse rates and decrease the number of lesions in the brain and spinal cord. Several different types of DMTs exist with distinct properties and mechanisms of action. This is beneficial because the clinical course of MS varies from individual to individual, and so treatment must be tailored to each individual's unique disease.Since the proportion of women with MS is larger than that of men, the concept of managing MS with DMT while also taking into account pregnancy and fertility issues constitutes an important discussion. DMT may be useful for treating MS, but it can have negative effects on a woman if she is pregnant, trying Keywords: Multiple Sclerosis; Pregnancy; Disease Modifying Therapy; Teratogenicity; Breastfeeding Multiple sclerosis (MS) is the most common inflammatory condition of the central nervous system. Disease modifying therapy (DMT) aims to reduce relapse rates and decrease the quantity of lesions in the brain and spinal cord. Since MS is more prevalent in women than men, it is important to be aware of the interplay between MS and pregnancy. As MS can engender sexual dysfunction, primarily in the form of decreased desire and fatigue, it thereby affects conception. Hormonal differences between women with MS compared to women without MS include an increase in follicle-stimulating hormone and luteinizing hormone, and a decrease in testosterone. While fluctuations in estrogen result in a reduction in MS relapse rates during pregnancy, a subsequent increase in the post-partum period is observed. The mechanism of action and side effects of DMTs are described in this paper, including interferon, glatiramer acetate, and some newer medications. Although there are no recommended guidelines on the use of DMTs during pregnancy, it is generally agreed upon to cease their use prior to conception if possible, and the decision to continue a DMT should take into account the benefits to the mother and the risks to the fetus. Comprehending the mechanisms of action and teratogenicity indices of DMTs is crucial in understanding their effects on MS during pregnancy, which is an important aspect of providing health care to women with this condition.Tarneer Johal, BSc 1 1 Faculty of Medicine, University of British Columbia ABSTRACT RÉSUMÉ La sclérose en plaques (SP) est l'affection inflammatoire du système nerveux central la plus commune. Le traitement modificateur de la maladie (DMT, de l'anglais) vise à réduire les taux de poussées et à diminuer le nombre de lésions au cerveau et à la moelle épinière. Comme la SP est plus prévalente chez les femmes que chez les hommes, il est important de reconnaître l'interaction entre la SP et la grossesse. Puisque la SP peut engendrer une dysfonction sexuelle, principalement en raison d'une diminution du désir sexuel et de la fatigue, elle affecte la conception...

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Effects of Multiple Sclerosis on Female Sexuality: A Controlled Study

Cited by 54 publications

References 38 publications

Autonomic dysfunction in multiple sclerosis

Autonomic dysfunction in multiple sclerosis

Correlates of Sexual Function in Male and Female Patients with Multiple Sclerosis

The Effects of Multiple Sclerosis and Disease Modifying Therapy on Pregnancy

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