Effects of montmorillonite on the structure and properties of gelatin‐polyethylene glycol composite fibers

Mu, Changdao; Li, Xinying; Guo, Jimin; Bi, Cai-Xia; Li, Defu

doi:10.1002/app.38808

Cited by 11 publications

(13 citation statements)

References 44 publications

(69 reference statements)

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“…Gelatin and Agel show the absorption peaks at 2935 and 2880 cm –1 , corresponding to C–H asymmetric and symmetrical stretching vibrations of the methylene, respectively. Gelatin and Agel both show the amide I band at 1640 cm –1 and amide II band at 1545 cm –1 . , Specifically, the intensities of amide absorption bands of Agel are obviously higher than that of gelatin, which may attributed to that more amide bands are formed between the gelatin and ED in Agel. Furthermore, Agel shows the higher absorption intensity at ∼2935 cm –1 .…”

Section: Resultsmentioning

confidence: 93%

“…Gelatin and Agel both show the amide I band at 1640 cm −1 and amide II band at 1545 cm −1 . 37,41 Specifically, the intensities of amide absorption bands of Agel are obviously higher than that of gelatin, which may attributed to that more amide bands are formed between the gelatin and ED in Agel. Furthermore, Agel shows the higher absorption intensity at ∼2935 cm −1 .…”

Section: Preparation Of Dialdehyde Carboxymethylmentioning

confidence: 96%

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Facile Fabrication of Biocompatible Gelatin-Based Self-Healing Hydrogels

Lei

Wang

et al. 2019

ACS Appl. Polym. Mater.

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147

109

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The self-healing hydrogels are extremely attractive in biological and biomedical fields. The imine bond obtained by the Schiff base reaction is a commonly used dynamic covalent bond to fabricate self-healing hydrogels. Gelatin is a commonly used natural macromolecule in the biomedical field with excellent biocompatibility, biodegradability, and nonimmunogenicity. However, the gelatin-based hydrogels with self-healing ability are rarely reported based on imine bonds. Herein, we present a facile approach to fabricate a gelatin hydrogel with self-healing ability based on the Schiff base reaction. The gelatin was first reacted with ethylenediamine to increase the content of amino groups. Then dialdehyde carboxymethyl cellulose was used to cross-link amino-gelatin to fabricate the self-healing hydrogel. The results showed that the fabricated hydrogel exhibited good self-healing ability as expected because of the formed dynamic imine bonds between amino-gelatin and dialdehyde carboxymethyl cellulose. The hydrogel also presented good fatigue resistance and self-recovery capacity. Moreover, the self-healing hydrogel possessed ideal hemocompatibility and cytocompatibility. In sum, the fabricated self-healing hydrogel has application prospects in biomedical fields, such as injectable cell and drug carrier and injectable tissue engineering scaffold.

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Section: Resultsmentioning

confidence: 93%

Section: Preparation Of Dialdehyde Carboxymethylmentioning

confidence: 96%

Facile Fabrication of Biocompatible Gelatin-Based Self-Healing Hydrogels

Lei

Wang

et al. 2019

ACS Appl. Polym. Mater.

Self Cite

147

109

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“…1,2 Among the various materials, gelatin is an inexpensive, neutral, water-soluble, non-toxic, and FDAapproved biopolymer with excellent biocompatibility, biodegradability, and cell adhesiveness, which is extensively used in medical products, such as wound dressings, drug delivery systems, and tissue engineering. [3][4][5][6][7][8][9][10][11][12] Until now, gelatin has been fabricated in various forms, e.g., lms, 13 nanoparticles, 14 and porous hydrogels. 15 There are several studies to produce functional gelatin bers by electrospinning, because of the high surface area, high porosity, and exibility for surface functionalization of gelatin based bers.…”

mentioning

confidence: 99%

“…10 Furthermore, the cross-sectional shape of electro-spun bers is almost exclusively limited to round shape due to interfacial tension between the solvent/ber material solution and air. 12 Although there have been some reports on fabrication of gelatin bers with relatively larger size by gel-spinning, the obtained bers are less-uniform, and this method does not allow for tuning of the cross-section and size. 4,16 It is well known that bers with complex shapes have improved mechanical properties and larger surface area, and are promising materials for biological microreactors, tissue engineering, and controlled release.…”

mentioning

confidence: 99%

On-chip development of hydrogel microfibers from round to square/ribbon shape

et al. 2014

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We use a microfluidic approach to fabricate gelatin fibers with controlled sizes and cross-sections. Uniform gelatin microfibers with various morphologies and cross-sections (round and square) are fabricated by increasing the gelatin concentration of the core solution from 8% to 12%. Moreover, the increase of gelatin concentration greatly improves the mechanical properties of gelatin fibers; the Young's modulus and tensile stress at break of gelatin (12%) fibers are raised about 2.2 and 1.9 times as those of gelatin (8%) fibers. The COMSOL simulations indicate that the sizes and cross-sections of the gelatin fibers can be tuned by using a microfluidic device with four-chevron grooves. The experimental results demonstrate that the decrease of the sheath-to-core flow-rate ratio from 150 : 1 to 30 : 1 can increase the aspect ratio and size of ribbon-shaped fibers from 35 μm × 60 μm to 47 μm × 282 μm, which is consistent with the simulation results. The increased size and shape evolution of the cross-section can not only strengthen the Young's modulus and tensile stress at break, but also significantly enhance the tensile strain at break. Disciplines Applied Mechanics | Biology and Biomimetic Materials | Biomechanical Engineering | Polymer and Organic MaterialsComments This is a manuscript of an article published as Bai, Zhenhua, Janet M. Mendoza Reyes, Reza Montazami, and Nastaran Hashemi. "On-chip development of hydrogel microfibers from round to square/ribbon shape."We use a microfluidic approach to fabricate gelatin fibers with controlled sizes and cross sections. Uniform gelatin microfibers with various morphologies and cross sections (round and square) are fabricated by increasing the gelatin concentration of core solution from 8 % to 12 %. Moreover, the increase of gelatin concentration greatly improves the mechanical properties of gelatin fibers; the Young's modulus and tensile stress at break of gelatin (12 %) fiber are raised about 2.2 and 1.9 times as those of gelatin (8 %) fiber. The COMSOL simulations indicate that the size and cross section of gelatin fiber can be tuned by microfluidic device with four-chevron grooves. The experiment results demonstrate that the decrease of sheath-to-core flow-rate ratio from 150:1 to 30:1 can increase the aspect ratio and size of ribbon-shaped fiber from 35 µm × 60 µm to 47 µm × 282 µm, which consists well with the simulation results. The increased size and shape evolution of cross section can not only strengthen the Young's modulus and tensile stress at break, and also significantly enhance tensile strain at break.

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“…MMT clay is a naturally occurring layered aluminosilicate with a large specific surface area, cation exchange capacity, and drug‐carrying capability, which make it suitable for the synthesis of polymer–clay nanocomposites . MMT clay can be incorporated into a polymer host matrix in order to control the diffusion rate of slow‐release material.…”

Section: Introductionmentioning

confidence: 99%

Nanoencapsulation of montmorillonite clay within poly(ethylene glycol) nanobeads by electrospraying

Mahmood

Azarian

Fathilah

et al. 2017

J of Applied Polymer Sci

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The present study describes the preparation and characterization of a novel nanocomposite, based on montmorillonite clay (MMT) encapsulation in poly(ethylene glycol) (PEG) by an electrospraying process. PEG/MMT nanocomposites with MMT contents ranging from 1 to 5 wt % were successfully prepared and characterized in relation to their morphological, spectroscopic, structural, and thermal properties. Scanning electron microscopy, transmission electron microscopy, and atomic force microscopy micrographs showed that the PEG nanobeads formed spherical shapes, and with increasing amount of MMT clay, the size of the beads decreased significantly, ranging from 120 to 3.7 nm. The Fourier transform infrared spectroscopy results suggested that there was no significant chemical interaction between PEG and MMT clay. However, the d‐spacing of MMT clay in PEG/MMT increased, a clear indication of the intercalation of PEG in the interlayer spaces of MMT clay. Furthermore, the thermal stability of PEG polymer decreased upon encapsulation of MMT clay in PEG/MMT composites. Nanoindentation results showed that the hardness and Young's modulus of the PEG/MMT composites increased with 3 wt % loading of MMT. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45048.

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Effects of montmorillonite on the structure and properties of gelatin‐polyethylene glycol composite fibers

Cited by 11 publications

References 44 publications

Facile Fabrication of Biocompatible Gelatin-Based Self-Healing Hydrogels

Facile Fabrication of Biocompatible Gelatin-Based Self-Healing Hydrogels

On-chip development of hydrogel microfibers from round to square/ribbon shape

Nanoencapsulation of montmorillonite clay within poly(ethylene glycol) nanobeads by electrospraying

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