Effects of monoglucoside and diglucoside anthocyanins from Yan 73 (Vitis vinifera L.) and spine grape (Vitis davidii Foex) skin on intestinal microbiota in vitro

Yue, Wenxiu; Han, Fei

doi:10.1016/j.fochx.2022.100501

Cited by 9 publications

(11 citation statements)

References 40 publications

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“…Furthermore, anthocyanins may alter the pH of the gut environment, thereby affecting microbial metabolic pathways and products. 82 These results provided insights into the interactions of VA or RA, gut microbiota, and SCFAs, while the mechanism is still unclear; further investigations are warranted to elucidate the potential mechanisms responsible for these effects and to investigate the potential effects of VA and RA in the context of gut microbiota and SCFAs. Functional prediction was conducted via PICRUSt2 software, which revealed that "metabolism" is the most critical metabolic pathway in the gut microbiota of the four groups.…”

Section: Discussionmentioning

confidence: 91%

“…Conversely, the relative abundance of Bacteroidetes, Verrucomicrobia, and Cyanobacteria was negatively correlated with SCFAs, suggesting that changes in these key phyla may contribute to the decrease in SCFA levels observed in the HVA and HRA groups. Furthermore, anthocyanins may alter the pH of the gut environment, thereby affecting microbial metabolic pathways and products . These results provided insights into the interactions of VA or RA, gut microbiota, and SCFAs, while the mechanism is still unclear; further investigations are warranted to elucidate the potential mechanisms responsible for these effects and to investigate the potential effects of VA and RA in the context of gut microbiota and SCFAs.…”

Section: Discussionmentioning

confidence: 95%

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Blueberry and Blackberry Anthocyanins Ameliorate Metabolic Syndrome by Modulating Gut Microbiota and Short-Chain Fatty Acids Metabolism in High-Fat Diet-Fed C57BL/6J Mice

Du,

Lü,

Chen

et al. 2023

J. Agric. Food Chem.

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In this study, blueberry (Vaccinium ssp.) anthocyanins (VA) and blackberry (Rubus L.) anthocyanins (RA) were used to investigate the effects on metabolic syndrome (MetS) and the potential mechanisms. Importantly, all of the data presented in this study were obtained from experiments conducted on mice. As a result, VA and RA reduced body weight gain and fat accumulation while improving liver damage, inflammation, glucose, and lipid metabolism induced by a high-fat diet. Moreover, VA and RA regulated the gut microbiota composition, decreasing the pro-obesity and proinflammation bacteria taxa, such as the phylum Actinobacterium and the genera Allobaculum and Bifidobacterium, and increasing those negatively associated with obesity and inflammation, such as the phylum Bacteroidetes and the genera Prevotella and Oscillospira. Additionally, the supplementation with VA and RA reversed the elevated levels of valeric, caproic, and isovaleric acids observed in the high-fat diet (HFD) group, bringing them closer to the levels observed in the Chow group. This reversal indicated that alterations in the composition and abundance of gut microbiota may contribute to the restoration of short-chain fatty acids (SCFAs) levels. Additionally, PICRUSt2 exhibited that cyanamino acid metabolism and betalain biosynthesis might be the major metabolic pathways in the HVA group compared with the HFD group, while in the HRA group, it was the phosphotransferase system. These findings suggest that VA and RA can ameliorate MetS by modulating the gut microbiota and production of SCFAs.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Blueberry and Blackberry Anthocyanins Ameliorate Metabolic Syndrome by Modulating Gut Microbiota and Short-Chain Fatty Acids Metabolism in High-Fat Diet-Fed C57BL/6J Mice

Du,

Lü,

Chen

et al. 2023

J. Agric. Food Chem.

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“…At the phylum level, our results indicated that Firmicutes and Bacteroides dominated the cecal microflora, which was consistent with the results of previous studies ( 61 , 62 ). The ratio of Firmicutes to Bacteroidetes is an important indicator of gut microbiota health ( 63 ), whereas inflammation and gut permeability improve when the ratio of Firmicutes to Bacteroides decreases ( 64 ). Studies have suggested that the addition of herbal medicines, such as CPO and AMT, decreases the ratio of Firmicutes to Bacteroidetes in weaned piglets ( 17 ), which is consistent with our results.…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary Astragalus membranaceus and Codonopsis pilosula extracts on growth performance, antioxidant capacity, immune status, and intestinal health in broilers

Liu,

Xiao,

Wang

et al. 2023

Front. Vet. Sci.

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The objective of this study was to examine the effects of dietary Chinese herbal medicine (CHM) consisting of Astragalus membranaceus (Fisch.) Bunge (AMT) and Codonopsis pilosula (Franch.) Nannf (CPO) extracts on growth performance, antioxidant capacity, immune status, and intestinal health of broiler chickens. Two groups were formed, each consisting of six replicates of 12 one-day-old healthy male 817 white feather broilers. Broilers were fed either a basal diet (CON group) or a basal diet supplemented with 500 mg/kg CHM. The trial lasted 50 days. The results showed that CHM supplementation resulted in enhanced feed efficiency and antioxidant capacity in both the serum and liver, while it reduced uric acid and endotoxin levels, as well as diamine oxidase activity (p < 0.05). Additionally, CHM treatment increased the height of jejunum villi and upregulated Claudin-1 expression in the jejunal mucosa accompanied by an increase in the mRNA levels of interleukin-6 (IL-6), interferon-γ (IFN-γ), interferon-β (IFN-β), tumor necrosis factor-α (TNF-α), and anti-inflammatory cytokine interleukin-10 (IL-10) (p < 0.05). The presence of dietary CHM caused an increase in the proportions of Bacteroidetes and unclassified Bacteroidales but led to a decrease in those of Firmicutes and Alistipes (p < 0.05). The composition of the jejunal mucosa microbiota was correlated with the feed conversion ratio, serum metabolites, and gene expression based on Spearman correlation analysis. The findings indicated that the consumption of dietary CHM improved the utilization of feed, increased the mRNA expression of pro-inflammatory cytokines in the jejunal mucosa, and decreased the endotoxin level and activities of diamine oxidase and lactate dehydrogenase in the serum, which could potentially be linked to changes in the gut microbiota of broiler chickens.

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“…Besides antioxidant activity, anthocyanins have exhibited many health benefits, for example, modulating gut microbiota, stimulating short‐fatty acids production in colon, and prevention of insulin fibrillation (Channuwong et al., 2022; Yue & Han, 2022). Numerous efforts have been performed on whole‐grain foods to utilize these bioactive phenolics.…”

Section: Introductionmentioning

confidence: 99%

Comparative study on nutritional and technological properties of two varieties of black wheat flour and their noodle‐making potential

Li,

Wang,

Niu

et al. 2023

Journal of Food Science

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Comparative studies were conducted on physicochemical and technological properties of two black wheat (BW) varieties (cultivated in Shanxi Agricultural University) and their noodle‐making potential. Whole‐grain BW noodles showed acceptable cooking loss (≤10%) and strong antioxidant capacity. However, their textural quality remains to be enhanced. Regarding refined flour (RF) of the two BW varieties, Yunhei 14207 showed more anthocyanins, brighter color, and greater thermal stability (as reflected by the higher pasting temperature). 16W16 resulted in greater gluten content and better gluten quality of flour and higher dough stability, which contributed to the lower cooking loss and stronger tensile property of noodles. RF noodles of Yunhei 14207 displayed brighter appearance, although they had weaker tensile property. The stronger gluten network in noodles of 16W16 protected phenolics from release and degradation during drying, cooking, and steaming. Despite phenolics loss, RF noodles of Yunhei 14207 showed antioxidant capacity up to 14.97 mg TE/100 g. This research would promote understanding of characteristics of BW varieties. Considering the stronger gluten network of 16W16, its fortification in common wheat noodles at high proportion (>50%) may be promising to develop antioxidant noodles with further improved sensory quality.

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Effects of monoglucoside and diglucoside anthocyanins from Yan 73 (Vitis vinifera L.) and spine grape (Vitis davidii Foex) skin on intestinal microbiota in vitro

Cited by 9 publications

References 40 publications

Blueberry and Blackberry Anthocyanins Ameliorate Metabolic Syndrome by Modulating Gut Microbiota and Short-Chain Fatty Acids Metabolism in High-Fat Diet-Fed C57BL/6J Mice

Blueberry and Blackberry Anthocyanins Ameliorate Metabolic Syndrome by Modulating Gut Microbiota and Short-Chain Fatty Acids Metabolism in High-Fat Diet-Fed C57BL/6J Mice

Effects of dietary Astragalus membranaceus and Codonopsis pilosula extracts on growth performance, antioxidant capacity, immune status, and intestinal health in broilers

Comparative study on nutritional and technological properties of two varieties of black wheat flour and their noodle‐making potential

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