Effects of Mono- and Dual Blockade of the Renin-Angiotensin System on Markers of Cardiovascular Status in Hypertensive Patients with Mild and Moderate Renal Failure
Abstract:Background/Aims: Dual renin-angiotensin system (RAS) blockade has no more efficiency to decrease cardiovascular mortality than mono-blockade. Our goal was to explore differences between other cardiovascular markers in patients with RAS blockade. Methods: We analyzed two groups of patients treated with a long-term ACE inhibitor (MONO-group, n = 20) and an ACE inhibitor and angiotensin II receptor blocker (DUAL-group, n = 15). Ambulatory blood pressure monitoring, echocardiography, arterial stiffness and levels … Show more
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