Effects of Methemoglobinemia on Pulse Oximetry and Mixed Venous Oximetry

Barker, Steven J.; Tremper, Kevin K.; Hyatt, John A.

doi:10.1097/00000542-198901000-00021

Cited by 323 publications

(70 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In COpoisoning readings erroneously will be close to normal. With most forms of methemoglobinemia SpO 2 is usually subnormal, but always >85% [8,9]. For unexplained reasons, favism seems to be a special case with spuriously low values <80%, which may affect clinical decisions as in our cases.…”

Section: Discussionmentioning

confidence: 61%

Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings

Leunbach

Pedersen

Trydal

et al. 2013

Pediatric Hematology and Oncology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 61%

Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings

Leunbach

Pedersen

Trydal

et al. 2013

Pediatric Hematology and Oncology

View full text Add to dashboard Cite

“…[4] It is reported that when MHb levels reach 30%–35%, the light absorbance reaches a plateau and the pulse oximeter reading becomes stable in the 82%–86% range. [456] ABG values can also be misleading. [7] The arterial PO 2 is a measure of dissolved oxygen and does not directly correlate with oxygen molecules bound to hemoglobin.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic dilemma: Low oxygen saturation during cardiac surgery

et al. 2017

View full text Add to dashboard Cite

We report a case of rheumatic heart disease with severe mitral stenosis having cyanosis and low oxygen saturation on pulse oximetry. The findings of clinical examination and low values on pulse oximetry were inconsistent with the findings of normal partial pressure of oxygen and oxygen saturation on arterial blood gas analysis, leading to diagnostic dilemma. In such clinical scenario, the anesthesiologist should be aware and vigilant about the differential diagnosis of low oxygen saturation on pulse oximetry.

show abstract

“…Conventional two wavelength pulse oximeters are not reliable to indicate the level of methaemoglobin concentration but typically there is a ‘saturation gap between the oxygen saturation on the pulse oximeter and the calculated haemoglobin oxygen saturation on the ABG 12. The ABG measures dissolved oxygen concentrations and so is unaffected by dyshaemoglobins.…”

Section: Discussionmentioning

confidence: 99%

Pop goes the O₂: a case of popper-induced methaemoglobinamia

2012

View full text Add to dashboard Cite

A 39-year-old man presented to the emergency department after falling downstairs after he consumed a large quantity of alcohol. On examination, he had altered mental state (GCS 14), central cyanosis and low oxygen saturation of 86%, despite 100% oxygen being administered. His arterial blood gas confirmed diagnosis of methaemoglobinaemia with a methaemoglobin percentage of 14.08. He was treated successfully with methylthioninium chloride. The patient later admitted to use of recreational poppers (amyl nitrates) the previous evening. The emergency physician is challenged by the presentation of a patient with altered mental state and unexplained low oxygen saturation with concurrent alcohol intoxication but must have a high index of suspicion for methaemoglobinaemia particularly with a history of recreational drug ingestion.

show abstract

Effects of Methemoglobinemia on Pulse Oximetry and Mixed Venous Oximetry

Cited by 323 publications

References 0 publications

Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings

Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings

Diagnostic dilemma: Low oxygen saturation during cardiac surgery

Pop goes the O₂: a case of popper-induced methaemoglobinamia

Contact Info

Product

Resources

About

Effects of Methemoglobinemia on Pulse Oximetry and Mixed Venous Oximetry

Cited by 323 publications

References 0 publications

Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings

Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings

Diagnostic dilemma: Low oxygen saturation during cardiac surgery

Pop goes the O2: a case of popper-induced methaemoglobinamia

Contact Info

Product

Resources

About

Pop goes the O₂: a case of popper-induced methaemoglobinamia