Effects of Methanolic and Aqueous Extracts of <i>Griffonia simplicifolia</i> (Fabaceae) on the Inhibition of Falciformation of Human Hb SS Erythrocytes
Abstract:Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and transportation of red blood cells (RBCs) in blood vessels, leading to various clinical complications. Sickle cell disease is a widespread genetic disease in Black Africa. The objective of this study was to evaluate the sickling inhibition activity of Griffonia simplicifolia. Quantitative and qualitative tests were used to determine the major groups of secondary metabolites present in the Griffonia simplicifolia leaves extracts and… Show more
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