Effects of metal contamination on liver in two fish species from a highly impacted neotropical river: A case study of the Fundão dam, Brazil

Weber, André Alberto; Sales, Camila Ferreira; Faria, Francisco de Souza; Melo, Rafael Magno Costa; Bazzoli, Nilo; Rizzo, Elizete

doi:10.1016/j.ecoenv.2020.110165

Cited by 61 publications

(19 citation statements)

References 41 publications

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“…and D. rhombeus was correlated with Cd, Cr, Hg, Mn and Zn, suggesting that metals create oxidative stress in those individuals ( Di Giulio et al, 1995 ; Atli & Canli, 2008 ; Monteiro et al, 2008 ; Sharma & Langer, 2014 ). Although GSH levels may vary among fish species, the species captured in the Rio Doce estuary exhibited higher GSH expression when compared to fish from uncontaminated freshwater ecosystems upstream ( Weber et al, 2020 ). In addition, fish species from contaminated freshwater ecosystems upstream exhibited similar oxidative stress effects, with higher biomarker levels in addition to internal tissue degeneration ( Weber et al, 2020 ; Macêdo et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

“…Although GSH levels may vary among fish species, the species captured in the Rio Doce estuary exhibited higher GSH expression when compared to fish from uncontaminated freshwater ecosystems upstream ( Weber et al, 2020 ). In addition, fish species from contaminated freshwater ecosystems upstream exhibited similar oxidative stress effects, with higher biomarker levels in addition to internal tissue degeneration ( Weber et al, 2020 ; Macêdo et al, 2020 ). The GSH expression in fish captured in the estuary suggests that local estuarine ecosystem health has also been severely compromised by trace metal contamination, with possible sub-optimal conditions for the development of fish species ( Andrades et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

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Contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster

Gabriel

Hauser‐Davis

Soares

et al. 2020

PeerJ

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Background The Rio Doce estuary, in Brazil, was impacted by the deposition of iron mine tailings, caused by the collapse of a dam in 2015. Based on published baseline datasets, the estuary has been experiencing chronic trace metal contamination effects since 2017, with potential bioaccumulation in fishes and human health risks. As metal and metalloid concentrations in aquatic ecosystems pose severe threats to the aquatic biota, we hypothesized that the trace metals in estuarine sediments nearly two years after the disaster would lead to bioaccumulation in demersal fishes and result in the biosynthesis of metal-responsive proteins. Methods We measured As, Cd, Cr, Cu, Fe, Mn, Pb, Se and Zn concentrations in sediment samples in August 2017 and compared to published baseline levels. Also, trace metals (As, Cd, Cr, Cu, Fe, Hg, Mn, Pb, Se and Zn) and protein (metallothionein and reduced glutathione) concentrations were quantified in the liver and muscle tissues of five fish species (Cathorops spixii, Genidens genidens, Eugerres brasilianus, Diapterus rhombeus and Mugil sp.) from the estuary, commonly used as food sources by local populations. Results Our results revealed high trace metal concentrations in estuarine sediments, when compared to published baseline values for the same estuary. The demersal fish species C. spixii and G. genidens had the highest concentrations of As, Cr, Mn, Hg, and Se in both, hepatic and muscle, tissues. Trace metal bioaccumulation in fish was correlated with the biosynthesis of metallothionein and reduced glutathione in both, liver and muscle, tissues, suggesting active physiological responses to contamination sources. The trace metal concentrations determined in fish tissues were also present in the estuarine sediments at the time of this study. Some elements had concentrations above the maximum permissible limits for human consumption in fish muscles (e.g., As, Cr, Mn, Se and Zn), suggesting potential human health risks that require further studies. Our study supports the high biogeochemical mobility of toxic elements between sediments and the bottom-dwelling biota in estuarine ecosystems.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster

Gabriel

Hauser‐Davis

Soares

et al. 2020

PeerJ

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“…Although GSH levels may vary among fish species, the fish captured in the Rio Doce estuary exhibited higher GSH expression when compared to fish in non-contaminated freshwater ecosystems upstream (Weber et al, 2020). In addition, contaminated freshwater ecosystems upstream exhibited similar effects of fish biomarker response (Weber et al, 2020) and…”

Section: Discussionmentioning

confidence: 92%

“…Queiroz et al (2018) hypothesized that the trace metals bound to Fe oxyhydroxides could become bioavailable upon Fe reduction in estuarine soils, leading to high ecological risks to the estuarine biota (Gabriel et al, 2020). The mobilization of trace metals from tailings have occurred in aquatic riverine ecosystems downstream of the ruptured mining dam (Weber et al, 2020). Our results support the relatively rapid metal bioaccumulation in liver and muscle tissues of fish in aquatic ecosystems, and support that biogeochemical conditions in estuarine sediments may promote bioavailability of metals bound to Fe from tailing in the sediments.…”

Section: Discussionmentioning

confidence: 99%

“…GSH expression in liver in C. spixii, E. brasilianus, Mugil sp., and D. rhombeus was correlated with Cd, Hg, Cr, Zn, and Mn, suggesting that GSH expression is related to oxidative stress caused by metals (Di Giulio et al, 1995;Atli & Canli, 2008;Monteiro et al, 2008;Sharma & Langer, 2014). Although GSH levels may vary among fish species, the fish captured in the Rio Doce estuary exhibited higher GSH expression when compared to fish in non-contaminated freshwater ecosystems upstream (Weber et al, 2020). In addition, contaminated freshwater ecosystems upstream exhibited similar effects of fish biomarker response (Weber et al, 2020) and…”

Section: Discussionmentioning

confidence: 99%

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Metal contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster

Gabriel

Hauser‐Davis

Soares

et al. 2020

Preprint

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AbstractThe Rio Doce estuary in Brazil was impacted by the deposition of mine tailings caused by the collapse of a mining dam in 2015. Since the disaster, the estuary is experiencing chronic trace metal contamination effects, but potential trace metal accumulation in fishes has not been reported. Trace metals in aquatic ecosystems pose severe threats to the aquatic biota, so we hypothesized that the accumulation of trace metals in estuarine sediments nearly two years after the disaster would cause contaminant bioaccumulation, resulting in the biosynthesis of metal-responsive proteins in fishes. We determined trace metal concentrations in sediment samples, metal concentrations, and quantified stress protein concentrations in the liver and muscle tissue of five different fish species in the estuary. Our results revealed high concentrations of trace metals in estuarine sediments when compared to published baseline values for this estuary. The demersal fish species Cathorops spixii and Genidens genidens had the highest Hg, As, Se, Cr, and Mn concentrations in both hepatic and muscle tissues. Metal bioaccumulation in fish was statistically correlated with the biosynthesis of metallothionein and reduced glutathione in both fish liver and muscle tissue. The trace metals detected in fish tissues resemble those in the contaminated sediments present at the estuary at the time of this study and were also significantly correlated to protein levels. Trace metals in fish muscle were above the maximum permissible limits for human consumption, suggesting potential human health risks that require further determination. Our study supports the high biogeochemical mobility of trace metals between contaminated sediments and local biota in estuarine ecosystems.

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Spatial–temporal variations of metals and arsenic in sediments from the Doce River after the Fundão Dam rupture and their bioaccumulation in Corbicula fluminea

Pauly

Cruz

Trevizani

et al. 2023

Integr Envir Assess & Manag

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The rupture of the Fundão dam in Brazil released tons of mining tailings into the Doce River Basin (DRB). This investigation aimed to determine the bioaccumulation of metals in soft tissues of the bivalve Corbicula fluminea exposed to sediments collected in the DRB in four periods (just after, 1, 3, and 3.5 years after the dam rupture). In the exposure bioassays, the concentrations of Al, As, Cd, Cr, Cu, Fe, Mn, Ni, Pb, and Zn in sediments and bivalve soft tissues were quantified. The concentration of some elements (As, Cd, Mn, and Al) in sediments exceeded the federal limits or regional backgrounds at some sampling sites, but their concentrations tended to decrease over time. However, higher concentrations of many elements were detected in the winter of 2019. Several elements were detected in C. fluminea soft tissues, but the bioaccumulation factors were generally low or not related to those elements associated with the ore tailings, evidencing that the bioavailability of metals to bivalves, in laboratory conditions, was limited. Integr Environ Assess Manag 2023;00:1–12. © 2023 SETAC

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Effects of metal contamination on liver in two fish species from a highly impacted neotropical river: A case study of the Fundão dam, Brazil

Cited by 61 publications

References 41 publications

Contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster

Contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster

Metal contamination and oxidative stress biomarkers in estuarine fish following a mine tailing disaster

Spatial–temporal variations of metals and arsenic in sediments from the Doce River after the Fundão Dam rupture and their bioaccumulation in Corbicula fluminea

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