Effects of Metabolic Syndrome on Early Mortality and Morbidity in Coronary Artery Bypass Graft Patients

Özyazicioğlu, Ahmet; Yalcinkaya, Serhat; Vural, A. Hakan; Yümün, Gündüz; Bozkurt, Oktay

doi:10.1177/147323001003800123

Cited by 13 publications

(23 citation statements)

References 26 publications

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“…Among coronary artery disease patients, its prevalence is 42.7% in males and 64.0% in females, with an overall prevalence of 53.0% 16. In our study, 42% of the patients had the MS, which is similar to other studies in MS patients undergoing CABG (42, 48, 47%) 11,12,17…”

Section: Discussionsupporting

confidence: 91%

“…Similar to previous studies,11,12,17,20 no significant difference was found in the occurrences of stroke and renal impairment after CABG between the MS and non-MS groups (p < 0.05). However, many parameters of morbidity, including AF, wound infection, pulmonary complications, prolonged intubation, and lengths of ICU and hospital stay were significantly higher in patients with the MS (p < 0.01).…”

Section: Discussionsupporting

confidence: 90%

“…Other studies reported similar mortality rates in the two patient groups 11,,1217. Swart et al11 compared 370 patients with the MS (as defined by the International Diabetes Federation and NCEP ATP III criteria) and 503 patients without the MS in terms of mortality and morbidity rates following CABG.…”

Section: Discussionmentioning

confidence: 96%

“…Özyazıcıoğlu et al12 examined the effects of the MS on postoperative mortality and morbidity rates in patients undergoing CABG. Compared with patients without the MS, those with the MS (NCEP ATP III criteria) had a higher incidence of wound infection (p < 0.05), but similar rates of atrial fibrillation, revision surgery due to haemorrhage, ventricular tachycardia, ventricular fibrillation, prolonged intubation and mortality rates.…”

Section: Discussionmentioning

confidence: 99%

“…Criteria used to define the MS may also lead to discrepant results, namely, cut-off points of criteria for the MS in various populations or even parameters of the MS (waist circumference instead of BMI) may vary. These differences may have a confounding effect on assessing the association between pre-operative MS and postoperative complications 11,12…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

The effects of the metabolic syndrome on coronary artery bypass grafting surgery

Özkan¹,

Özdemir²,

Uğur³

et al. 2017

CVJA

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SummaryBackgroundThe metabolic syndrome (MS) is a clustering of factors that are associated with increased cardiovascular risk. A low-grade inflammatory process acts as the underlying pathophysiology, which suggests that the MS may have a detrimental effect on coronary interventions, including coronary artery bypass grafting (CABG) surgery performed with cardiopulmonary bypass (CPB). We aimed to evaluate the effect of the MS on morbidity and mortality rates in the early postoperative period in patients undergoing CABG.MethodsWe prospectively included 152 patients (109 males and 43 females; mean age 60.1 ± 8.6 years) who underwent elective CABG on CPB between January and September 2011. Early postoperative morbidity and mortality rates were compared between subjects with and without the MS. Diagnosis of the MS was based on the American National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria.ResultsOf the study group, 64 patients (42%) had the MS. The two groups were similar in age and gender. In the postoperative period, rates of atrial fibrillation, wound infection, pulmonary complications, and lengths of intubation, hospitalisation and intensive care unit stay were significantly higher in MS patients (p < 0.01). The MS was significantly associated with wound infection (OR 6.64, 95% CI: 1.72–25.75), pulmonary complications (OR 6.44, 95% CI: 1.58–26.33), arrhythmia (OR 5.47, 95% CI: 1.50–19.97) and prolonged intubation (OR 1.17, 95% CI: 1.05–1.32). The mortality rate was 3.1% in the MS group and 1.1% in the non-MS group, with no significant difference (p > 0.05).ConclusionThe MS was associated with a higher rate of early postoperative morbidity following CABG, without having a significant effect on the mortality rate.

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Section: Discussionsupporting

confidence: 91%