Abstract:The objective of this work was to determine the repercussion of the metabolic changes that occur in induced subclinical pregnancy toxemia in single-or twin-bearing ewes on the duration of gestation, type and length of lambing, and placental expulsion time. Fifty-one adult Corriedale ewes with a known gestation date and fed in the wild were randomly divided at day 145 of gestation into four groups. Group A included single-bearing ewes, and C twin-bearing ewes, all of which were fed ad libitum. Group B was compo… Show more
“…At the time when ewes in groups B and D reached glycaemia values indicative of subclinical gestational toxaemia (28. 62±4.33mg/dL;Cal Pereyra et al, 2015), they were removed from feed restriction and switched to pasture feeding with natural pasture (Abreu-Palermo et al, 2021).…”
Section: Methodsmentioning
confidence: 99%
“…At day 145 of gestation, prior to the start of feed restriction, glycaemia concentration did not show significant differences among the experimental groups (A = 50.53±1.68 mg/dL; B = 55.13±2.14 mg/dL, C = 57.17±2.67 mg/dL, and D = 51.27±2.73 mg/dL). The glycaemia concentration of ewes in groups B (single gestation) and D (twin gestation) decreased 12 h after the start of feed restriction (P<0.001), reaching glycaemia values indicative of subclinical gestational toxaemia 48 h after the start of treatment (B = 30.67±2.37 mg/dL and D = 28.40±3.39 mg/dL) (Table 1; Abreu-Palermo et al, 2021).…”
Section: Metabolic Parameters In Ewesmentioning
confidence: 99%
“…At day 145 of gestation, before starting feed restriction, BHB concentration did not show significant differences among experimental groups (A = 0.69±0.05 mmol/L, B = 0.47±0.07 mmol/L, C = 0.72±0.14 mmol/L, and D = 0.85±0.20 mmol/L). The serum BHB concentration of ewes in the groups subjected to feed restriction (groups B and D) showed an increase (P = 0.0001) 24 h after starting the treatment, reaching serum values of this ketone body indicative of subclinical gestational toxaemia 48 h after starting the treatment (B = 1.87±0.12 mmol/L and D = 2.21±0.42 mmol/L) (Table 1; Abreu-Palermo et al, 2021). The absence of uppercase or lowercase letters implies the lack of significant differences among times or groups.…”
Section: Metabolic Parameters In Ewesmentioning
confidence: 99%
“…The subclinical form of the disease is characterised by steadily increasing hypoglycaemia and hyperketonemia in dams in the absence of clinical signs (Barbagianni et al, 2015b;Cal-Pereyra et al, 2015;Marutsova and Marutsov, 2017). At the blood level it can be diagnosed when glycaemia values are between 24.29 and 32.95 mg/dL at which time the serum concentration of β-hydroxybutyrate (BHB) is between 1.23 and 3.29 mmol/L (Abreu-Palermo et al, 2021). However, the effect of subclinical gestational toxaemia on lamb survival is not known.…”
The objective of this study was to determine the impact of metabolic changes occurring in induced subclinical gestation toxaemia in ewes on metabolic parameters and vigour in the first 72 h of their lambs' life. Fifty-one adult Corriedale ewes of known gestation date and fed on a natural pasture were randomly divided into four groups at day 145 of gestation. Group A (ewes with single pregnancies) and group C (ewes with twin pregnancies) were fed on a natural pasture throughout the trial; group B (ewes with single pregnancies) and group D (ewes with twin pregnancies) were subjected to 75% feed restriction for three days until they reached glycaemia and β-hydroxybutyrate (BHB) values indicative of subclinical gestational toxaemia. The birth-to-first station and birth-to-first suckling times of the born lambs were studied. Within the first hour after parturition and at 24, 48, and 72 h, glycaemia and BHB concentrations were determined in the blood of lambs, and body temperature and body weight were assessed at the same time. Relative weight gain at 72 h of age was calculated for all lambs. The BHB concentration determined at all times studied showed no difference among the groups. Subclinical gestation toxaemia induced in ewes subjected to feed restriction causes a decrease in the glycaemia of their lambs in the first hour of life; however, it does not cause an increase in ketone bodies. The metabolic changes induced in the mothers do not have negative effects on the vigour of the lambs at birth, as the weight, temperature, and the time it took for lambs to stand and suckle are not affected. However, they have a negative effect on relative weight gain in the critical period of the first 72 h of life.
“…At the time when ewes in groups B and D reached glycaemia values indicative of subclinical gestational toxaemia (28. 62±4.33mg/dL;Cal Pereyra et al, 2015), they were removed from feed restriction and switched to pasture feeding with natural pasture (Abreu-Palermo et al, 2021).…”
Section: Methodsmentioning
confidence: 99%
“…At day 145 of gestation, prior to the start of feed restriction, glycaemia concentration did not show significant differences among the experimental groups (A = 50.53±1.68 mg/dL; B = 55.13±2.14 mg/dL, C = 57.17±2.67 mg/dL, and D = 51.27±2.73 mg/dL). The glycaemia concentration of ewes in groups B (single gestation) and D (twin gestation) decreased 12 h after the start of feed restriction (P<0.001), reaching glycaemia values indicative of subclinical gestational toxaemia 48 h after the start of treatment (B = 30.67±2.37 mg/dL and D = 28.40±3.39 mg/dL) (Table 1; Abreu-Palermo et al, 2021).…”
Section: Metabolic Parameters In Ewesmentioning
confidence: 99%
“…At day 145 of gestation, before starting feed restriction, BHB concentration did not show significant differences among experimental groups (A = 0.69±0.05 mmol/L, B = 0.47±0.07 mmol/L, C = 0.72±0.14 mmol/L, and D = 0.85±0.20 mmol/L). The serum BHB concentration of ewes in the groups subjected to feed restriction (groups B and D) showed an increase (P = 0.0001) 24 h after starting the treatment, reaching serum values of this ketone body indicative of subclinical gestational toxaemia 48 h after starting the treatment (B = 1.87±0.12 mmol/L and D = 2.21±0.42 mmol/L) (Table 1; Abreu-Palermo et al, 2021). The absence of uppercase or lowercase letters implies the lack of significant differences among times or groups.…”
Section: Metabolic Parameters In Ewesmentioning
confidence: 99%
“…The subclinical form of the disease is characterised by steadily increasing hypoglycaemia and hyperketonemia in dams in the absence of clinical signs (Barbagianni et al, 2015b;Cal-Pereyra et al, 2015;Marutsova and Marutsov, 2017). At the blood level it can be diagnosed when glycaemia values are between 24.29 and 32.95 mg/dL at which time the serum concentration of β-hydroxybutyrate (BHB) is between 1.23 and 3.29 mmol/L (Abreu-Palermo et al, 2021). However, the effect of subclinical gestational toxaemia on lamb survival is not known.…”
The objective of this study was to determine the impact of metabolic changes occurring in induced subclinical gestation toxaemia in ewes on metabolic parameters and vigour in the first 72 h of their lambs' life. Fifty-one adult Corriedale ewes of known gestation date and fed on a natural pasture were randomly divided into four groups at day 145 of gestation. Group A (ewes with single pregnancies) and group C (ewes with twin pregnancies) were fed on a natural pasture throughout the trial; group B (ewes with single pregnancies) and group D (ewes with twin pregnancies) were subjected to 75% feed restriction for three days until they reached glycaemia and β-hydroxybutyrate (BHB) values indicative of subclinical gestational toxaemia. The birth-to-first station and birth-to-first suckling times of the born lambs were studied. Within the first hour after parturition and at 24, 48, and 72 h, glycaemia and BHB concentrations were determined in the blood of lambs, and body temperature and body weight were assessed at the same time. Relative weight gain at 72 h of age was calculated for all lambs. The BHB concentration determined at all times studied showed no difference among the groups. Subclinical gestation toxaemia induced in ewes subjected to feed restriction causes a decrease in the glycaemia of their lambs in the first hour of life; however, it does not cause an increase in ketone bodies. The metabolic changes induced in the mothers do not have negative effects on the vigour of the lambs at birth, as the weight, temperature, and the time it took for lambs to stand and suckle are not affected. However, they have a negative effect on relative weight gain in the critical period of the first 72 h of life.
“…In well-nourished pregnant ewes, either carrying singletons or twin fetuses, blood glucose concentration range is around 29-59 mg/dL during gestation (21), and around 40-60 mg/dL near term (22). The values recorded in our study for maternal glycaemia 1 week before delivery were in the range to those previously described in animals under a severe nutritional restriction [sheep with only 25% of the daily ration for 24-48 h (22)] in which glycaemia decrease to around 41 and 28 mg/dL for single-and twin-bearing ewes, respectively. Blood glucose content in our study increased in the peripartum to more than 3-fold higher than 1 week before parturition, again without differences due to the type of parturition.…”
Section: Maternal Glycemia and Reproductive Hormonesmentioning
Maternal nutrition during gestation plays an important role in colostrum production, postnatal growth, and survival of newborn lambs, especially in twin gestations. This research aimed to investigate the effects of chronic natural undernutrition on colostrum traits and early lamb’s postnatal growth born from single and twin sheep pregnancies developed in a restrictive prairie, representative of southern Patagonia. Single- and twin-bearing ewes (n = 20 per group) were maintained grazing in a natural pasture. At 140 days of gestation, ewes were placed in individual pens for lambing control. Colostrum was collected immediately after delivery and at 12, 24, and 36 h postpartum, for determination of yield and composition. Maternal blood was obtained at 140 days of gestation and at lambing for plasma glucose, progesterone, 17β-estradiol, and IgG determination. Newborn lamb blood for determining glycaemia and IgG was collected at birth and at 12, 24, 36, and 120 h after birth. Lamb mortality and growth was assessed from birth until 30 days of life. No differences were observed in progesterone and 17β-estradiol. There were no differences in colostrum yields and fat components, however single- had higher values of protein and lactose than twin-bearing ewes (p < 0.05 for both). Singletons had higher glycaemia than twins at 12 h postpartum (102.2 ± 32.8 vs. 73.4 ± 29.9 mg/dL, p < 0.05). Colostrum IgG content was similar at delivery but higher in single ewes at 12 and 24 h, reaching a similar values at 36 h (4.7 ± 9.7 and 5.8 ± 7.7 mg/mL in single and twin pregnancies, respectively). Newborn IgG was higher in singletons compared to twins at least until 48 h of life. Lams body weight was always superior in singleton than twins from birth until 30 days of life. Mortality did not differ during the first week of life, but it increased significantly only in twins until day 30 of life. Undernourishment in pregnant ewes affected colostrum quantity and quality, resulting in a lower postnatal growth and a higher mortality in twins. Alternative managements favoring fetal growth, birth weight and neonatal viability in twin sheep pregnancies are needed, when flocks are breed under harsh environments.
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