Effects of Manganese Hydroxychloride on Growth Performance, Antioxidant Capacity, Tibia Parameters and Manganese Deposition of Broilers

Abstract

This study was conducted to investigate the effects of dietary supplementation with manganese hydroxychloride (MHC) on production performance, antioxidant capacity, tibial quality, and manganese (Mn) deposition of broilers. A total of 756 one-day-old male Arbor Acres broilers were randomly allotted to 7 treatments of 6 replicates with 18 broilers per replicate. Broilers were fed corn-soybean meal basal diets supplemented of 100 mg/kg Mn as Mn sulfate (MnSO4), or 0, 20, 40, 60, 80, 100 mg/kg Mn as MHC for 42 days. The growth performance of broilers was not affected by dietary MnSO4 or MHC (p > 0.05), whereas the dressing percentage increased linearly (p < 0.05) with increasing of dietary MHC addition level. The activities of catalase (CAT) and manganese superoxide dismutase (MnSOD), and total antioxidant capability (T-AOC) in serum and liver on day 42 increased linearly (p < 0.05) with increasing of dietary MHC level, while malondialdehyde (MDA) concentration reduced linearly (p < 0.05). The length, strength, and density index of tibia increased linearly (p < 0.05) on day 21 as MHC supplementation level increased; there were no differences between MnSO4 group and 40–100 mg/kg Mn as MHC groups in tibial parameters of broilers (p > 0.05). As supplemental MHC levels increased, the Mn contents in heart, liver, kidney, and tibia increased linearly on day 42 (p < 0.05). In summary, dietary supplementation with MHC improved antioxidant capacity, bone quality, and Mn contents in broilers, but no effects on growth performance were detected. Based on the results of this study, dietary inclusion of 50–90 mg/kg Mn in the form of MHC to broilers is recommended.

Impacts of Biosynthesized Manganese Dioxide Nanoparticles on Antioxidant Capacity, Hematological Parameters, and Antioxidant Protein Docking in Broilers

“…54 The recent research on the effects of manganese on broiler blood parameters highlights its significant benefits. Manganese supplementation has been found to enhance hemoglobin levels, 52,53 and boost immune function. 54 These findings underscore the importance of incorporating adequate manganese levels in broiler diets to optimize blood health and overall performance.…”

“…Studies have revealed that Mn supplementation positively influences white blood cell counts, lymphocyte proliferation, and antibody production, thereby enhancing the immune system's ability to combat pathogens. 52,53 Furthermore, Mn has been found to promote the synthesis of immunoglobulin, which contributes to the humoral immune response. 54 The recent research on the effects of manganese on broiler blood parameters highlights its significant benefits.…”

“…Manganese has been shown to play a pivotal role in modulating immune responses, particularly with broiler blood parameters. Studies have revealed that Mn supplementation positively influences white blood cell counts, lymphocyte proliferation, and antibody production, thereby enhancing the immune system’s ability to combat pathogens. , Furthermore, Mn has been found to promote the synthesis of immunoglobulin, which contributes to the humoral immune response …”

Influence of Water Quality and Pollution on Broiler’s Performance, Vaccine and Antibiotic Efficiencies – A Review

“…According to Salem et al (2001), more than 0.05 mg/l of manganese was present in 58.97% of the water samples taken from Assiut, Egypt. Excessive manganese levels have been linked to water flavor issues (Carter and Sneed, 1996;Sun et al, 2021). Coetzee et al (2000) discovered that manganese levels in poultry drinking water in the Western Cape survey ranged from 27.15 g/L to 2204.7 g/L.…”

“…Noticeably, manganese concentrations are positively associated with the quantity of iron in the groundwater in Scotland (Homoncik et al, 2010;Sun et al, 2021). Manganese levels greater than the SMCL of 0.05 mg/L will result in black flecks or stains, metallic-tasting water, and standing water that appears gray or black (Swistock and Clark, 2012).…”