Effects of Local Laser Treatment on Vulvovaginal Atrophy for Women With Breast Cancer: A Prospective Study With Long-Term Follow-Up

Veron, Lucie; Wehrer, Delphine; Annerose-Zéphir, Gisèle; Chaltiel, Dan; Delaloge, Suzette; Pistilli, Barbara; Pautier, Patricia

doi:10.26226/morressier.5fa3ee5d55b1fd4cc4dd93d5

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“…В недавних исследованиях акцентируется значительное влияние реабилитации на сексуальное здоровье и общее КЖ женщин с различной гинекологической патологией и злокачественными новообразованиями репродуктивной системы, что подчеркивает необходимость назначения комплексной «активной» реабилитации, направленной как на физические, так и на психологические аспекты KЖ [3][4][5][6]. Вмешательства с использованием негормональных методов, таких как CO2-лазер, показали свою эффективность в улучшении симптомов ВВА и повышении КЖ у женщин с раком молочной железы, что еще раз указывает на потенциальную пользу реабилитационных мероприятий [7]. Однако существует пробел в лонгитудинальных исследованиях влияния восстановительных мероприятий на КЖ пациенток с ВВА.…”

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The impact of rehabilitation on the quality of life of patients with vulvovaginal atrophy

Ampilogova,

Solopova,

Blinov

et al. 2024

Akušerstvo, ginekologiâ i reprodukciâ

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Aim: to evaluate the impact of rehabilitation on various components of quality of life (QoL) in patients with vulvovaginal atrophy (VVA).Materials and Methods. A prospective comparative controlled longitudinal study involved 350 patients with VVA, divided into groups based on the type of menopause: surgical (n = 140) and natural (n = 140), with a control group of 70 women without VVA. Patients were further subdivided into those receiving complex "active" (groups 1A, 2A) and "passive" (groups 1B, 2B) rehabilitation. The study included 6 visits over 24 months, assessing QoL using the Female Sexual Function Index (FSFI), Hospital Anxiety and Depression Scale (HADS), Modified Menopausal Index (MMI), Well-being, Activity, Mood questionnaire (WAM), Magnesium Deficiency Questionnaire (MDQ), and the Assessment Test of Magnesium Deficiency (ATMD).Results. Women with surgical menopause had severe sexual dysfunction initially. Complex "active" rehabilitation significantly improved sexual function over time compared to "passive" rehabilitation. Surgical menopausal women had higher initial levels of anxiety and depression. "Active" rehabilitation significantly reduced these levels, reaching normal values within the first year. Patients with surgical menopause exhibited more severe menopausal symptoms. "Active" rehabilitation led to significant reductions in these symptoms, improved well-being, activity, and mood more significantly than "passive" rehabilitation, particularly in the first year. Complex "active" rehabilitation normalized magnesium deficiency indicators within three months, maintaining normal levels throughout the study.Conclusion. Comprehensive "active" rehabilitation significantly improves sexual function, reduces anxiety and depression, alleviates menopausal symptoms, and enhances overall well-being in women with VVA, especially those in surgical menopause. Personalized rehabilitation programs are crucial for enhancing QoL in these patients.

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