Effects of lighting environment on the degeneration of retinal ganglion cells in glutamate/aspartate transporter deficient mice, a mouse model of normal tension glaucoma
Abstract:Lighting conditions may affect the development of retinal degenerative diseases such as macular degeneration. In this study, to determine whether the lighting environment affects the progression of degeneration of retinal ganglion cells (RGCs), we examined glutamate/aspartate transporter (GLAST) heterozygous (GLAST
+/-
) mice, a mouse model of normal tension glaucoma. GLAST
+/-
mice were reared under a 12-h light-dark cycle (Light/Dark) or complete darkness (Dark/D… Show more
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