Effects of Leishmania major infection on the gut microbiome of resistant and susceptible mice
Jakub Mrázek,
Lucie Mrázková,
Chahrazed Mekadim
et al.
Abstract:Cutaneous leishmaniasis, a parasitic disease caused by Leishmania major, is a widely frequent form in humans. To explore the importance of the host gut microbiota and to investigate its changes during L. major infection, two different groups of mouse models were assessed. The microbiome of two parts of the host gut—ileum and colon—from infected and non-infected mice were characterised by sequencing of 16S rDNA using an Ion Torrent PGM platform. Microbiome analysis was performed to reveal changes related to the… Show more
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