Effects of L-carnitine administration on $$\dot V_{o_{2{\text{ }}max} } $$ and the aerobic-anaerobic threshold in normoxia and acute hypoxia

Wyss, V; Ganzit, Gian Pasquale; Rienzi, A.

doi:10.1007/bf00572178

Cited by 52 publications

(30 citation statements)

References 22 publications

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“…20 Other studies also support that L-carnitine has no effect on blood glucose levels. 21 What distinguishes this study from the aforementioned studies is the level and time of L-carnitine consumption. The results of the present study also suggest that 3 g of L-carnitine supplementation has no effect on blood glucose levels.…”

Section: Discussionmentioning

confidence: 96%

Acute Effect of L-Carnitine Supplements on Lactate, Glucose, Saturated Oxygen and VO2max Variations in Young Males

Kashef¹,

Saei²

2017

Int J Basic Sci Med

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Introduction: L-carnitine may improve athlete's performance by increasing lipids oxidation. The goal of the present study was to assess the acute impact of L-carnitine supplements on lactate, glucose, saturated oxygen and VO 2 max levels in young men. Methods: Ten young males completed 2 sessions of exhausting exercise (Bruce test). In the first session, the participants consumed placebo and in the second session, they consumed 3 g of L-carnitine 90 minutes before the test. The 2 sessions were 1-week apart. Then dependent parameters were measured. Results: A significant difference was detected in VO 2 max and lactate between the placebo and supplement groups (P < 0.05) but the difference between glucose, saturated oxygen and heart rate was not statistically significant (P > 0.05) between the 2 groups. Conclusion: The present study showed that L-carnitine supplementation before exercise decreases lactate and increases VO 2 max in young men.

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Section: Discussionmentioning

confidence: 96%

Acute Effect of L-Carnitine Supplements on Lactate, Glucose, Saturated Oxygen and VO2max Variations in Young Males

Kashef¹,

Saei²

2017

Int J Basic Sci Med

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“…De hecho, algunos autores como Lancha, et.al 8 y Wyss, et.al 25 consideran que la suplementación de la L-carnitina en ratas entrenadas por medio de ejercicios de larga duración retardan la fatiga muscular, así como también, se sugiere el uso para la prevención del daño de los músculos esqueléticos 26 , aumento de la regulación del flujo sanguíneo y la distribución de O 2 para el tejido muscular durante y después del ejercicio físico 27 , respectivamente.…”

Section: Discussionunclassified

Efectos de la suplementación de carnitina sobre el nivel de fatiga muscular del gastrocnemio de ratas entrenadas y sedentárias

Gomez

Arruda

Ramos

et al. 2012

Rev. Bras. Cineantropom. Desempenho Hum.

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BY Efectos de la suplementación de carnitina sobre el nivel de fatiga muscular del gastrocnemio de ratas entrenadas y sedentarias Effect of carnitine supplementation on fatigue level in the gastrocnemius muscle of trained and sedentary ratsRossana Gomez Campos Resumo -La L-carnitina tiene un gran valor en procesos metabólicos al cumplir un papel importante en el proceso de β-oxidación mitocondrial, por lo cual, podría ser usada para mejorar el rendimiento atlético y mantener una carga de trabajo. Este trabajo tuvo por objetivo evaluar los efectos de la suplementación de L-carnitina y del entrenamiento en el tiempo necesario a la inducción de la fatiga muscular en preparaciones in situ del nervio ciático y músculo gastronemio en ratas. Cuatro grupos de animales fueron constituidos: sedentario no suplementado (SNS), sedentario suplementado (SS), entrenado no suplementado (ENS) y entrenado suplementado (ES). El entrenamiento fue realizado en sesiones diarias (1h/5dias/semana) y con suplementación oral crónica de L-Carnitina (1mg/ml) por 4 semanas. La fatiga muscular fue obtenida mediante estimulación supramaximal tetánica del nervio ciático (50 Hz). Los valores del tiempo para la reducción de fuerza fueron significativamente diferentes (p<0,05) entre los grupos SNS vs SS y ENS vs ES, respectivamente. Sin embargo, no hubo diferencias significativas entre los grupos ES vs SS y ENS vs SNS. Estos resultados demuestran que la L-carnitina prolongo el tiempo necesario para la reducción de fuerza a nivel del músculo gastrocnemio.

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“…2010;54/1 Carnitina e substratos energéticos jam disponíveis, como ocorre nos exercícios de baixa a moderada intensidade (27).…”

Section: Discussionunclassified

“…(27) avaliaram os efeitos da suplementação de L-carnitina (3 g/dia) durante sete dias sobre o VO 2máx em condições de hipóxia e normóxia em 7 homens saudáveis. O consumo máximo de oxigênio foi menor na hipóxia, mas sem diferenças significativas para os dois tratamentos (carnitina e placebo).…”

Section: Discussionunclassified

A suplementação de L-carnitina não promove alterações na taxa metabólica de repouso e na utilização dos substratos energéticos em indivíduos ativos

Coelho

Mota

Ravagnani

et al. 2010

Arq Bras Endocrinol Metab

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A suplementação de L-carnitina não promove alterações na taxa metabólica de repouso e na utilização dos substratos energéticos em indivíduos ativosThe supplementation of L-carnitine does not promote alterations in the resting metabolic rate and in the use of energetic substrates in physically active individuals To investigate the effects of L-carnitine supplementation, over thirty days, on the resting metabolic rate (RMR) and oxidation of free fatty acids (FFA) under rested or exercised conditions. Subjects and methods: Twenty-one overweight active volunteers (40 to 58 years old) were randomized into two groups: supplemented (GS; N = 11; 1,8 g/day of L-carnitine) or placebo (GP; N = 10; maltodextrin). Caloric intake, anthropometry, RMR, VO 2max , respiratory exchange ratio and plasma FFA were measured. Results: No significant changes were found in the caloric intake (-244,66 vs. -126,00 kcal/day), body composition (-0.07 vs. -0.17 kg/m 2 ), RMR (0.06 vs. -0.02 kcal/day), respiratory exchange ratio at rest (3.69 vs. -1.01) and exercise (0.01 vs. -0.01) or VO 2max (0.50 vs. 1.25 mL/kg/min) between GS and GP. Plasma FFA levels were increased under resting conditions only in the GP group (0.27), but no significant changes were observed before or after physical activity in any of the groups. Conclusion: Supplementation with L-carnitine caused no changes in the variables analyzed in this study. Arq Bras Endocrinol Metab. 2010;54(1):37-44

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Effects of L-carnitine administration on $$\dot V_{o_{2{\text{ }}max} } $$ and the aerobic-anaerobic threshold in normoxia and acute hypoxia

Cited by 52 publications

References 22 publications

Acute Effect of L-Carnitine Supplements on Lactate, Glucose, Saturated Oxygen and VO2max Variations in Young Males

Acute Effect of L-Carnitine Supplements on Lactate, Glucose, Saturated Oxygen and VO2max Variations in Young Males

Efectos de la suplementación de carnitina sobre el nivel de fatiga muscular del gastrocnemio de ratas entrenadas y sedentárias

A suplementação de L-carnitina não promove alterações na taxa metabólica de repouso e na utilização dos substratos energéticos em indivíduos ativos

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