Effects of isolated obesity on left ventricular function: a longitudinal strain imaging study

Abdelazez, Walaa F; Yaseen, Rehab; Alkersh, Ahmed M.; Ebada, Mohammad A.H.

doi:10.4103/1110-2098.132785

Cited by 4 publications

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“…In the current study the results showed that E, A and E/A values did not differ across the spectrum of obesity and this agree with a study was done in Spain by Pascual et al to 48 obese persons and 25 non obese subjects with range age (14-54 years), found the E, A, and E/A ratio did not differ (18) . Also in concordance with another study was done in Egypt by Walaa F. et al to 65 individuals with isolated obesity, and 20 non obese, found no significant difference between individuals regarding E velocity, A velocity, and E/A ratio (19). Across sectional study was carried out in Nineveh-Iraq by Amjad Fawzy et al to 146 individuals from both sexes(85 male and 61 female) aged 20-59 years, observed a significant decrease in both maximum velocity of passive mitral filling (E) and E/A ratio, and increasing in the A wave (20) Bello and colleagues in Italy, found increasing in the A wave, decreasing in the E/A ratio and no change in the E wave in 48 persons(11 males, 37 females) all without a history of medical disease (21) .In the present study p-values were significant in both sexes, but in males more than females.…”

Section: Discussionsupporting

confidence: 91%

“…Contrary to the current study, another study was done by Giovanni et al in the united states to show the differences in relations between BMI in 1068 men and 1851 women and left ventricular function, found obesity influences left ventricular function substantially more in women than in men, possibly due to different in sample size (22) . In this study, the deceleration time of the mitral valve was significantly prolonged in obese subjects and correlated inversely with BMI which is in accordance with a study was done in India to show the diastolic dysfunction in individuals with isolated obesity by Praveen Kumar, et al to two hundred subjects in the age group of 21-61 years, (23) and disagree with Pascual et al (18) , while a study in Egypt by Ahmed Shalaby et al found no statistical difference in deceleration time (24) .Moreover, the results showed that LAD increases significantly with BMI and agree with a study was done in Brazil by Isaura et al (25) , also Walaa F. et al, observed the obese participants had significantly increased left atrial diameter (19) . Amjad et al, (20) , and agree with this results.…”

Section: Discussionmentioning

confidence: 72%

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Effect of Body Mass Index on Left Ventricular Diastolic Function

Rgeeb¹

2018

Kufa Jour. Nurs. Sci.

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Introduction: Overweight and obese persons are at increased risk for heart failure. A direct effect of isolated obesity on cardiac function is not well established.Objective: To assess the independent effect of increased body mass index on the left ventricular diastolic function. Methodology: cross sectional study to measure of the left ventricular diastolic function was carried out on (175) apparently healthy persons from both sex (68 female and 107 male) aged between 26-49 years (37.5±9.5). Personnel without any other pathological condition were studied. The study sample was divided into 3 groups according to their body mass index (kg/m²): [normal (18.5-24.9), overweight (25-29.9) & obese ( % 30)]. Echocardiographic indices of left diastolic function were obtained, and dysfunction was assumed when at least two values differed by % 2 SD from the normal weight group.Results: Diastolic dysfunction was significantly higher in overweight and obese groups compared to the normal body mass index group. The deceleration time was with significant P-value (<0.01) and left atrial diameter (p< 0.01) was more in obese persons, while other diastolic variables were unchanged. No differences were found between obesity subgroups. Body mass index correlated significantly with indices of left ventricular diastolic function.Conclusions: Subclinical left ventricular diastolic dysfunction was noted in all grades of obesity which correlates with body mass index, and more significant in males than females.Recommendations: people who are suffering from obesity are recommended for follow up and assessment, also they are in need for encouragement to active participation in weight reduction programs.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 72%

Effect of Body Mass Index on Left Ventricular Diastolic Function

Rgeeb¹

2018

Kufa Jour. Nurs. Sci.

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Obesity and Cardiac Remodeling in Adults: Mechanisms and Clinical Implications

Alpert

Karthikeyan

Abdullah

et al. 2018

Progress in Cardiovascular Diseases

157

111

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An echocardiographic study of the effect of obesity on systolic and diastolic functions of the left ventricle in hypertensive adults

Shree

Prashanth

Girija

2022

IJPP

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Objectives: The objectives of the study were to examine the effect of obesity on echocardiographic parameters of systolic and diastolic functions of the left ventricle (LV) in asymptomatic hypertensive adults. Materials and Methods: A cross-sectional study was conducted with 100 individuals (65 males and 35 females). Their blood pressure and body mass index were recorded following which they were divided into obese hypertensives and non-obese hypertensives. Echocardiographic examination was done, and parameters indicating LV geometry and function were recorded. Data were statistically analysed for differences. An unpaired t-test was used considering P < 0.05 as a significant value. Results: Echocardiographic parameters of LV diastolic function were significantly altered in obese hypertensives compared to non-obese hypertensives (P < 0.05). About 58% of non-obese hypertensives and 78% of obese-hypertensives had LV diastolic dysfunction. About 6% of non-obese hypertensives and 8% of obese-hypertensives had LV systolic dysfunction. Conclusion: Obesity in hypertensive individuals adds risk for diastolic dysfunction. The number of subjects falling into categories of mild-to-moderate diastolic dysfunction was considerably higher in the obese hypertensives compared to the non-obese hypertensives.

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Effects of isolated obesity on left ventricular function: a longitudinal strain imaging study

Cited by 4 publications

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Effect of Body Mass Index on Left Ventricular Diastolic Function

Effect of Body Mass Index on Left Ventricular Diastolic Function

Obesity and Cardiac Remodeling in Adults: Mechanisms and Clinical Implications

An echocardiographic study of the effect of obesity on systolic and diastolic functions of the left ventricle in hypertensive adults

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