2019
DOI: 10.21203/rs.2.15636/v2
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Effects of iron on the growth, biofilm formation and virulence of Klebsiella pneumoniae causing liver abscess

Abstract: Background: Klebsiella pneumoniae is considered the most clinically relevant species of Enterobacteriaceae, known to cause severe infections including liver abscesses. To the best of our knowledge, a large proportion of iron in the human body is accumulated and stored in the liver. We hypothesize that increased iron availability is an important factor driving liver abscess formation and we therefore aim to understand the effects of iron on K. pneumoniae causing liver abscesses. Results: All tested K. pneumon… Show more

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