Effects of Ionizing Radiation on the Hair-bulbs of Young Rats

Smoliar, V.

doi:10.1080/09553006614550751

Cited by 5 publications

(2 citation statements)

References 10 publications

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“…previously observed in order to evaluate radiation and drug effects (Van Scott 1958, Argyris & Chase 1966, Smoliar 1966, Albert etal. 1967, Burns etal.…”

Section: Discussionmentioning

confidence: 99%

Surface Architecture of X‐lrradiated Hair Follicles

Klein‐Szanto

Rey

1978

J Cutan Pathol

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The combined use of scanning electron-microscopy and chemical separation of epidermis permitted the study of the irradiated and normal hair follicle surface characteristics. Irradiation reduced the length and density of the hair follicles, producing at the same time marked alterations and deformities of the individual follicles. As most of these changes were dose- and time-dependent, these structures, studied by these techniques, provide an interesting model as biological indicators of radiation dose.

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“…previously observed in order to evaluate radiation and drug effects (Van Scott 1958, Argyris & Chase 1966, Smoliar 1966, Albert etal. 1967, Burns etal.…”

Section: Discussionmentioning

confidence: 99%

Surface Architecture of X‐lrradiated Hair Follicles

Klein‐Szanto

Rey

1978

J Cutan Pathol

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“…This procedure has been used to study events within the proximal portions of hair follicles (Cattaneo et al 1961; McCarter and QuastIer 1962; Smoliar 1966; Epstein and Maibach 1969), and some aspects of cell proliferation, migration and sloughing in wool follicles (Downes et al 1966;Chapman 1971; Vsevolodov and Prusova 1976).…”

Section: Introductionmentioning

confidence: 99%

Migration and Keratinization of Cells in Wool Follicles

Chapman¹,

Downes²,

Pa³

1980

Aust. Jnl. Of Bio. Sci.

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. .Migration of' cells in wool follicles of an adult Merino sheep was studied autoradiographically in skin samples taken at intervals after an intravenous injection of [3Hjthymidine. Fibre arid inner root sheath cells incorporated [3Hjthymidine in a cone-shaped region of the follicle bulb. Labelled inner sheath cells migrated out of the bulb ahead of contemporaneous cells in the fibre and remained in advance, although to a progressively lesser extent, until the inner sheath cells sloughed into the follicle lumen. Outer root sheath cells incorporated [3Hjthymidine along the length of the follicle. Cells in the proximal half of the outer sheath migrated inwards and distally and sloughed into the follicle lumen before contemporaneous inner sheath cells. Other cells in the distal half of the outer sheath migrated past the level where cells from the proximal population were shed and also sloughed into the lumen. In the most distal part of the outer sheath, which formed the epidermis-like lining of the follicle canal, little migration of cells was observed during 8 days of observation.The specific activity of tritium in fibres plucked from the same sheep at intervals after the intravenous injection of [3Hjthymidine was determined by scintillation counting and assessed in terms of cell migration and hardening of the fibres. The time at which the specific activity of solventdegreased fibres reached a maximum was found to give an estimate of the time for cells in the fibre to migrate to the upper limit of the keratogenous zone. When the plucked fibres were extracted with 8 M urea the times of the maximum specific activities of the urea-dispersible and urea-insoluble material provided respectively estimates of the times at which hardening of the fibres began and ended.The effects of different planes of nutrition were examined in two other Merino sheep by radioassay· of fibres plucked after intravenous injections of [3Hjthymidine given after an equilibration period of at least 2 months on each level of feeding. A high plane of nutrition increased the rate of cell migration and hastened the onset of hardening of the fibres, but prolonged the hardening process. The prolongation of the hardening process was confirmed by the specific activities of fibres plucked after intravenous inje,

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Influence of X-irradiation on the different stages of the cell cycle in regenerating rat liver

Barbason¹

1974

Arch Otorhinolaryngol

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Effects of Ionizing Radiation on the Hair-bulbs of Young Rats

Cited by 5 publications

References 10 publications

Surface Architecture of X‐lrradiated Hair Follicles

Surface Architecture of X‐lrradiated Hair Follicles

Migration and Keratinization of Cells in Wool Follicles

Influence of X-irradiation on the different stages of the cell cycle in regenerating rat liver

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