Effects of iodine deficiency on mental and psychomotor abilities

Bleichrodt, N.; Drenth, P.J.D.; Querido, A

doi:10.1002/ajpa.1330530110

Cited by 35 publications

(14 citation statements)

References 7 publications

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“…These test results were consistent with previous studies that reported higher scores on perceptual motor tasks in individuals from iodine-replete versus iodine-deficient populations (e.g. Bleichrodt et al 1980). The Raven Progressive Matrices test has been used successfully in other studies of iodine deficiency and results have demonstrated the psychological advantage of an iodinesufficient environment (Ma et al 1989).…”

Section: Discussionsupporting

confidence: 90%

Effects of iodine supplementation during pregnancy on child growth and development at school age

O’Donnell

Rakeman

Zhi-Hong

et al. 2002

Develop Med Child Neuro

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Growth and development of 207 children (49% males; mean age 5.4 years [SD 0.2], range 4 to 7.3 years whose mothers received iodine during pregnancy, and children who received iodine first in their 2nd year, were examined in 1996; 192 children(49% males; mean age 6.5 years[SD 0.2], range 5.8 to 6.9 years) whose mothers received iodine while pregnant were seen in 1998. Children were from the southern part of China's Xinjiang Province which has the lowest levels of iodine in water and soil ever recorded. Head circumference but not height was improved for those who received iodine during pregnancy (compared with those receiving iodine at age 2) and for those supplemented before the end of the 2nd trimester (relative to those supplemented during the 3rd trimester). Iodine before the 3rd trimester predicted higher psychomotor test scores for children relative to those provided iodine later in pregnancy or at 2 years. Results from the test for cognitive development resulted in trend only differences between those children supplemented during pregnancy versus later. The results address the question of when maternal iodine supplements should begin in public health programs world wide. Findings may be relevant to the treatment of maternal and newborn thyroid deficiency in industrialized countries, particularly for those infants delivered before the end of the second trimester.

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Section: Discussionsupporting

confidence: 90%

Effects of iodine supplementation during pregnancy on child growth and development at school age

O’Donnell

Rakeman

Zhi-Hong

et al. 2002

Develop Med Child Neuro

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“…Similar results have been obtained in Bolivia (32) and in Papua New Guinea (33). Bleichrodt et al carried out intensive studies in central Java and found that administration of iodine improved the results of tests of fine motor control, but changes in intellectual function were not convincing (34,35). Their study was marred by differences in educational attainments between the villages that were tested.…”

Section: Patterns Of Cretinismsupporting

confidence: 63%

Nutritional Deficiency Disorders

Stanbury

1985

Food Nutr Bull

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Endemic goitre continues to be a major public health problem in many of the developing countries. Probably a quarter of the world's population is at risk. In many endemias, especially those of India and central Africa, the disease and its accompanying disorders are responsible for serious disability and contribute to economic and social backwardness. While mild endemic goitre constitutes no particular disadvantage, when moderately severe or severe, the larger goitres may be a serious burden to the medical care system, and the attendant cretinism and lesser degrees of neuromuscular and intellectual impairment are surely important iodine deficiency disease is readily preventable by measures that are cost effective. Low viability of the disorder on the one hand and governmental inattention on the other are responsible for continued high prevalence rates. While there is ample information to support immediate implementation of prophylactic programmes in regions of endemic iodine deficiency disease, there remain interesting questions for research, the answers to some of which at least might affect the design and execution of prophylactic programmes and would certainly advance our understanding of iodine deficiency disease.

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“…The question arises as to whether this situation could have an influence on the long term ncurointellectual development of the affected infants. Such a possibility has been clearly demonstrated in areas with an ex tremely severe iodine deficiency [19][20][21],…”

Section: Discussionmentioning

confidence: 99%

Regional Variations of Iodine Nutrition and Thyroid Function during the Neonatal Period in Europe

Delange¹,

Heidemann

Bourdoux³

et al. 1986

Neonatology

120

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In order to evaluate further the possibility that transient hypothyroidism and hyperthyrotropinemia in newborn infants could result from a state of relative iodine deficiency, the urinary concentration of iodine, used as an index of the dietary intake of iodine was determined in casual urine samples collected in 1,076 full-term infants aged 3–6 days in 16 cities in 10 different European countries and in Toronto, Canada. In addition, the results obtained by programs of systematic neonatal screening for congenital hypothyroidism in the same areas were compared. There were marked regional differences in iodine nutrition during the neonatal period in Europe (median urinary iodine: 16.2 μg/dl in Rotterdam, the Netherlands, and 1.1 μg/dl in Freiburg, FRG. A low iodine supply in newborn populations was accompanied by, and probably explained, an elevated frequency of transient disorders of thyroid function in young infants. Iodine prophylaxis is urgently needed in some European countries not only for the prevention of goiter, but mostly for the prevention of impairment of thyroid function during the critical period of brain development.

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Effects of iodine deficiency on mental and psychomotor abilities

Cited by 35 publications

References 7 publications

Effects of iodine supplementation during pregnancy on child growth and development at school age

Effects of iodine supplementation during pregnancy on child growth and development at school age

Nutritional Deficiency Disorders

Regional Variations of Iodine Nutrition and Thyroid Function during the Neonatal Period in Europe

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