Effects of intravenous and topical laryngeal lidocaine on heart rate, mean arterial pressure and cough response to endotracheal intubation in dogs

The effects of intravenous lidocaine before propofol induction in premedicated dogs

“…Finally, the required dose of propofol was not significantly different (P=0.081) between the two groups. This latter observation is in agreement with the findings of Braun et al (), Kraus & Cazlan (), and Thompson & Rioja (). The lack of significant differences between groups may be related to the limitations of this study, which include the technique used for blood pressure monitoring, influence of premedication drugs, the sensitivity of the different scoring systems, the hand injection of propofol and the limited sample size.…”

“…Finally, the required dose of propofol was not significantly different (P=0.081) between the two groups. This latter observation is in agreement with the findings of Braun et al ( 2007 ), Kraus & Cazlan ( 2015 ), and Thompson & Rioja ( 2015 ). The lack of significant differences Table 3 .…”

“…Parasympathetic stimulation involving the vagal reflex has been implicated in the neonate after nasopharyngeal stimulation, because of the afferent vagal fibres in the pharynx, oesophagus and respiratory tract (Marshall et al ). In dogs a sympathetic response has been most commonly described in the literature (Jolliffe et al , Thompson & Rioja ). In our study, HR increased at the time of intubation in group P but remained stable in group L, resulting in a significant interaction between treatment and time for HR.…”

“…In healthy non‐premedicated dogs, the administration of diazepam (0.25 mg/kg) or lidocaine (2 mg/kg) IV, 2 minutes before induction of anaesthesia with propofol, did not reduce the propofol dose required for loss of jaw tone, but effects on endotracheal intubation were not reported (Braun et al , Minghella et al ). To the authors’ knowledge, only a few studies have compared the influence of lidocaine versus saline on adverse effects during endotracheal intubation in dogs (Jolliffe et al , Kraus & Cazlan , Thompson & Rioja ). Thompson & Rioja () demonstrated that lidocaine (2 mg/kg) administered IV during propofol induction (first dose of propofol followed by treatment with either saline or lidocaine, and then a further dose of propofol “to effect”), in methadone‐premedicated dogs (0.2 mg/kg IV) attenuated the pressor and cough response to endotracheal intubation.…”

ARRIVE and CONSORT guidelines: do they have a place in Veterinary Anaesthesia and Analgesia?

“…Veterinary Anaesthesia and Analgesia's current peer review questionnaire takes into account many points common to the reporting guidelines detailed above. The editors have the impression that manuscripts adhering to the guidelines have a smoother ride through the peer review and editorial process and would like to thank the authors who have recently submitted or revised their manuscripts to conform to CONSORT or ARRIVE (Campagna et al 2015;Conde Ruiz et al 2015;Nalon et al 2015;Sarotti et al 2015;Thompson & Rioja 2015;Prasse et al 2016).…”