Effects of intraoperative administration of carbohydrates during long-duration oral and maxillofacial surgery on the metabolism of carbohydrates, proteins, and lipids

Yamamoto, Toru; Yoshida, Mitsuhiro; Watanabe, Seiji; Kawahara, Hiroshi

doi:10.1007/s10006-015-0517-2

Cited by 5 publications

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3-methylhistidine is a metabolite of arginine, lysine, and histidine without being recycled for protein synthesis and is excreted in the urine. It is possible to evaluate the degree of catabolism and use it as an indicator of the turnover of muscle protein [11][12][13][14] . We thus measured blood glucose and the urinary concentration of 3-methylhistidine.…”

Section: Discussionmentioning

confidence: 99%

Effect of Preoperative Carbohydrate and Amino Acid Infusion on Postoperative Counter-Regulatory Hormone in Patients Undergoing Elective Thoracoscopic Esophagectomy

Motegi

Murakami

Otsuka

et al. 2016

Showa Univ J Med Sci

View full text Add to dashboard Cite

: Compared with the conventional open surgery, thoracoscopic esophagectomy results in decreased thorax destruction, fewer postoperative complications, and shorter hospitalisation. However, preoperative fasting causes hyperglycemia, prompting attempts to improve postoperative hyperglycemia by preoperatively administering carbohydrate orally or intravenously. Herein, we examined the effect of preoperative carbohydrate and amino acid infusion on counter-regulatory hormone levels in patients undergoing elective thoracoscopic esophagectomy. The glucose and amino acid GA group n 12 were infused with a low concentration of sugar accelerant and amino acid, and the control GAF group n 12 was infused with a sugar-free extracellular uid, until entering the operating room. We evaluated plasma catecholamine 3 fractions, cortisol, and glucose, as well as 3-methylhistidine in the urine. Adrenaline levels were signi cantly higher in the GAF group 263.0 201.8 µIU / ml than in the GA group 114.7 127.0 µIU / ml at the end of the surgery P 0.042 , and at postoperative day POD 1 200.8 137.4 vs. 80.5 64.3 µIU / ml ; P 0.013 . The noradrenalin level was also significantly higher in the GAF group 517.9 523.6 µIU / ml than in the GA group 254.3 205.4 µIU / ml at POD1 P 0.028 , as was the cortisol level 20.0 10.6 µIU / ml vs. 10.2 8.0 µIU / ml ; P 0.015 . No signi cant differences were observed between the two groups in levels of blood glucose or 3-methylhistidine in the urine. Preoperative glucose-amino acid administration improved catabolism suppression in this study.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Preoperative Carbohydrate and Amino Acid Infusion on Postoperative Counter-Regulatory Hormone in Patients Undergoing Elective Thoracoscopic Esophagectomy

Motegi

Murakami

Otsuka

et al. 2016

Showa Univ J Med Sci

View full text Add to dashboard Cite

show abstract

“…Использование низкоконцентрированных растворов глюкозы (1-1,25%) для проведения инфузионной тера-пии во время оперативных вмешательств в отоларинголо-гии челюстно-лицевой хирургии сопровождалось более низким уровнем СГ, ИР и катаболизма белка [55,56].…”

Section: профилактика и коррекция послеоперационной ирunclassified

Post-operative insulin resistance

Tarasova¹,

Shestakov²,

Zubova³

2017

Diabetes mellitus

View full text Add to dashboard Cite

Вопросы патогенезаPathogenesis настоящее время под инсулинорезистентностью (ИР) понимают снижение биологического от-вета к одному или нескольким эффектам дей-ствия инсулина [1]. Наиболее часто ИР определяют как состояние, которое сопровождается снижением ути-лизации глюкозы тканями в ответ на действие инсулина, т.е. резистентностью органов и тканей к сахароснижаю-щему действию инсулина [2].Феномен ИР был описан в 1939 г. Himsworth H.P. и Kerr R.B. для определения недостаточного ответа на введение экзогенного инсулина у больных сахар-ным диабетом 2 типа (СД2) и ожирением [3]. В даль-нейшем ИР была выявлена и при других состояниях у пациентов без предшествующего СД, например при беременности, уремии, после обширных травм, ожо-гов [4][5][6]. Инсулинорезистентность после хирургических вмешательств

show abstract

Prognosis for major abdominal surgeries based on intraoperative low-dose nutrition: A metabolic perspective

Satoh,

Takeuchi,

Kawagoe

et al. 2023

Clinical Nutrition ESPEN

View full text Add to dashboard Cite

Effects of intraoperative administration of carbohydrates during long-duration oral and maxillofacial surgery on the metabolism of carbohydrates, proteins, and lipids

Cited by 5 publications

References 13 publications

Effect of Preoperative Carbohydrate and Amino Acid Infusion on Postoperative Counter-Regulatory Hormone in Patients Undergoing Elective Thoracoscopic Esophagectomy

Effect of Preoperative Carbohydrate and Amino Acid Infusion on Postoperative Counter-Regulatory Hormone in Patients Undergoing Elective Thoracoscopic Esophagectomy

Post-operative insulin resistance

Prognosis for major abdominal surgeries based on intraoperative low-dose nutrition: A metabolic perspective

Contact Info

Product

Resources

About