Effects of intermittent duration of ultrasound exposure on temperature rise and behavior of cavitation bubbles in bubble-enhanced ultrasonic heating

Ito, Sayaka; Umemura, Shin‐ichiro; Yoshizawa, Shin

doi:10.1250/ast.41.913

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2024

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“…Previous studies have investigated the heating efficiency of bubble-enhanced ultrasonic heating using tissue-mimicking gels. [31][32][33] Bubbles generated in a tissue were observed by using a hybrid phantom consisting of tissue and agarose gel. 33) However, temporal changes in the region of cavitation bubble generation in bubble-enhanced ultrasonic heating have not been studied.…”

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confidence: 99%

Effect of intended shift in propagation direction of cavitation generation position on coagulation position in bubble-enhanced ultrasonic heating

Kannoto,

Yoshizawa

2024

Jpn. J. Appl. Phys.

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High-intensity focused ultrasound (HIFU) treatment is a noninvasive cancer treatment that uses powerful focused ultrasound energy to coagulate tissue, but it has the problem of time-consuming treatment due to its small focal region. Therefore, we pay attention to the heating effect of cavitation bubbles. The safe use of bubbles in treatment requires that they be reliably generated and maintained in the treatment region. In this study, the effects of the HIFU focal shift in the direction of ultrasound propagation on the bubble and coagulation regions were investigated by high-speed camera imaging and ultrasound imaging. As a result, the appropriate focal shift of pulses that generates the bubbles prevented expansion of bubble regions and generated coagulation regions with good reproducibility near the position to be treated.

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