Effects of Interfacial Redox in Mussel Adhesive Protein Films on Mica

Yu, Jing; Wei, Wei; Danner, Eric; Israelachvili, Jacob N.; Waite, J. Herbert

doi:10.1002/adma.201003580

Cited by 155 publications

(220 citation statements)

References 26 publications

Supporting

Mentioning

211

Contrasting

Unclassified

Order By: Relevance

“…Our analyses by CD are limited to detecting a random coil at solution conditions consistent to those present during secretion. 39 Perhaps, a random coil conformation of mfp-3 in solution is beneficial for anticipating a variety of conformations adopted on different surface chemistries.…”

Section: Discussionmentioning

confidence: 99%

Three intrinsically unstructured mussel adhesive proteins, mfp‐1, mfp‐2, and mfp‐3: Analysis by circular dichroism

Hwang

Waite

2012

Protein Science

Self Cite

View full text Add to dashboard Cite

Mussel foot proteins (mfps) mediate fouling by the byssal holdfast and have been extensively investigated as models for versatile polymer-mediated underwater adhesion and coatings. However, insights into the structural properties of mfps have lagged far behind the nanomechanical advances, owing in part to the inability of these proteins to crystallize as well as their limited solubility. Here, solution secondary structures of mfp-1, mfp-2, and mfp-3, localized in the mussel byssal cuticle, adhesive plaque, and plaque-substratum interface, respectively, were investigated using circular dichroism. All three have significant extended coil solution structure, but two, mfp-1 and mfp-2, appear to have punctuated regions of structure separated by unstructured domains. Apart from its punctuated distribution, the structure in mfp-1 resembles other structural proteins such as collagen and plant cell-wall proteins with prominent polyproline II helical structure. As in collagen, PP II structure of mfp-1 is incrementally disrupted by increasing the temperature and by raising pH. However, no recognizable change in mfp-1's PP II structure was evident with the addition with Ca 21 and Fe 31 . In contrast, mfp-2 exhibits Ca 21 -and disulfidestabilized epidermal growth factor-like domains separated by unstructured sequence. Mfp-2 showed calcium-binding ability. Bound calcium in mfp-2 was not removed by chelation at pH 5.5, but it was released upon reduction of disulfide bonds. Mfp-3, in contrast, appears to consist largely of unstructured extended coils.

show abstract

Section: Discussionmentioning

confidence: 99%

Three intrinsically unstructured mussel adhesive proteins, mfp‐1, mfp‐2, and mfp‐3: Analysis by circular dichroism

Hwang

Waite

2012

Protein Science

Self Cite

View full text Add to dashboard Cite

show abstract

“…!" ), the bidentate hydrogen bonding of catechol to mica (-E = ~28 kT) would have a binding lifetime (τ) that is 10 6 times longer than the monodentate form (-E = ~14 kT) [50,52,53].…”

Section: Iron Coordination By Biological Catechols Catechol Siderophoresmentioning

confidence: 99%

“…5a) [56]. Measured adhesive forces of Mfps are considerably lower at pH 5.5 and in most cases adhesion is completely abolished above pH 7.5 [29,40,43,52]. pH-dependent oxidation of Dopa has been implicated in the pH dependence of Mfp adhesion [29,50,52].…”

Section: Surface Interactions Of Catecholmentioning

confidence: 99%

See 1 more Smart Citation

Siderophores and mussel foot proteins: the role of catechol, cations, and metal coordination in surface adhesion

Maier

Butler

2017

J Biol Inorg Chem

View full text Add to dashboard Cite

Metal coordination, hydrogen bonding, redox reactions, and covalent crosslinking are seemingly disparate chemical and physicochemical processes that are all accomplished in natural materials by the catechol functional group. This review focuses on the reactivity of catechols in tris-2,3-dihydroxybenzoyl-containing microbial siderophores and synthetic analogs, as well as Dopa-(3,4-dihydroxyphenylalanine)-containing mussel foot proteins that adhere to surfaces in aqueous conditions.Mussel foot proteins with a high content of Dopa and cationic amino acids, Lys and Arg, adhere strongly to mica, an aluminosilicate mineral, in aqueous conditions. The siderophore cyclic trichrysobactin, tris-(2,3-dihydroxybenzoyl-D-Lys-L-Ser) and related synthetic analogs in which the tri-Ser macrolactone is replaced by Tren, tris-(2-aminoethyl)amine, also adheres strongly to mica. Variation in the nature of the catechol and cationic groups in synthetic analogs reveals a synergism between the cationic amino acid and the catechol, required for strong aqueous adhesion. Autoxidation and iron(III)-catalyzed oxidation of 2,3-dihydroxy and 3,4-dihydroxy catechols is also considered. These siderophore analogs provide a platform to understand catechol interactions and reactivity on surfaces, which may ultimately improve the design of synthetic materials that address diverse challenges in medicine, materials science, as well as other disciplines, in which surface adhesion in aqueous conditions is important.

show abstract

“…[13,48] In addition, the 3,4-dihydroxyphenylalanine (DOPA)-rich proteins in the mussel byssal plaque, such as mfp-3 (20 mol% DOPA) and mfp-5 (28 mol% DOPA), coordinated with Fe 3+ , enable the plaque to adhere to rocks containing metal ions under water. [13,[49][50][51][52] In conclusion, mussel byssal displays multi functional features, such as self-healing and adhesion, with different types of metal coordination interactions.…”

Section: Interface Interactionsmentioning

confidence: 93%

High‐Performance Nanocomposites Inspired by Nature

2017

View full text Add to dashboard Cite

Over the eons of evolutionary time, natural materials, including nacre, bone, lobster cuticle, and many others, developed delicate multiscale structures demonstrating outstanding properties. These natural materials provide endless inspiration for the fabrication of novel bioinspired structural materials. Extensive research has revealed the mechanism responsible for natural materials' properties and shows that high-performance structural materials could be fabricated via bioinspired strategies. [1][2][3][4][5][6][7][8][9][10] With the quest to develop novel bioinspired materials, it is essential to refine some basic scientific principles that can guide bioinspired fabrication.Recent research has indicated that the amplification of natural materials' mechanical properties far beyond those of the components that comprise them originates mainly from: i) a hierarchical micro-/nanoscale architecture and ii) abundant effective interface interactions. Here, we follow the roadmap of "discovery, invention, and creation," as shown in Figure 1, to give insight into the development of bioinspired structural materials. In the "discovery" section, natural materials are described as a source of inspiration. Bioinspired nanocomposites can be invented to mimic or even to surpass natural materials' attributes, as described in the "invention" section. We illustrate how the basic principles could work for bioinspired nanocomposites with different building blocks and fabrication approaches. Finally, in the "creation" section, we review novel multifunctional nanocomposites with properties that natural materials rarely possess. To provide a vision and inspiration for future research, we conclude with our perspectives on new and promising directions in the field, along with problems remaining to be solved. Discovery: Natural Materials Orderly Hierarchical ArchitecturesNatural materials are made at ambient temperatures from a relatively small number of ingredients that exhibit rather meager properties. Almost all of them are composites with orderly hierarchical architectures that arrest crack propagation, thus preventing catastrophic failure. Insight into the architecture of a typical natural material is the key to understanding the superiority of the biomimetic strategy for making novel synthetic materials.Natural materials, including nacre, bone, and the lobster cuticle, exhibit excellent mechanical properties, combining high strength and toughness. Such materials have the added benefit of being light in weight. These advantageous features are due to such natural materials' orderly hierarchical architectures and abundant interface interactions. How to utilize these design principles created by nature to fabricate high-performance bioinspired nanocomposites remains a great research challenge. A logical roadmap for developing these nanocomposites can be described as "discovery, invention, and creation." Here, the discovery of the relationship between natural materials' design principles and such materials' extraordinary mechanical proper...

show abstract

Effects of Interfacial Redox in Mussel Adhesive Protein Films on Mica

Cited by 155 publications

References 26 publications

Three intrinsically unstructured mussel adhesive proteins, mfp‐1, mfp‐2, and mfp‐3: Analysis by circular dichroism

Three intrinsically unstructured mussel adhesive proteins, mfp‐1, mfp‐2, and mfp‐3: Analysis by circular dichroism

Siderophores and mussel foot proteins: the role of catechol, cations, and metal coordination in surface adhesion

High‐Performance Nanocomposites Inspired by Nature

Contact Info

Product

Resources

About