Effects of Intake of Astaxanthin Contained Drink on Skin Condition

Abstract

Objectives: To study the effect of astaxanthin contained drink to skin condition Methods: The study was conducted to the Japanese females between age over thirty to less than fifty, who had weakening of skin (including aging, sag and dry skin) and skin dullness. In order to conduct the objective evaluation, the comparison between the groups by the double-blind test was taken. Twenty of subjects were randomly allocated to the intake group of astaxanthin contained drink (astaxanthin 3mg contained) and the placebo group. After eight weeks intake of the drink, each group was evaluated with skin water contents, transepidermal water loss, skin elasticity, VISIA and skin texture etc. Results: In between the groups, the intake group of astaxanthin contained drink was greatly excellent in the categories of skin moisture, transepidermal water loss, skin elasticity, erythema dose and skin texture. Conclusion: Astaxanthin has protecting effect of skin barrier and is considered to increase the water retention capability to reduce skin dryness. Astaxanthin is also effective to erythema dose, skin elasticity and skin texture. As no adverse events resulting from the test drink was seen, such food containing astaxanthin is considered as a safe and useful health functional food material to skin.

In Vitro Evaluation of Skin-Related Physicochemical Properties and Biological Activities of Astaxanthin Isomers

“…Several clinical trials showed that astaxanthin on the dermal layer contributed to the improvement of wrinkles. ,− This indicates that astaxanthin serves to maintain the extracellular matrix (ECM) of the dermis layer. In particular, it is believed that astaxanthin quenches singlet molecular oxygen, , which is involved in the damage of collagen-based ECM-producing fibroblasts, and also inhibits enzymatic activities and/or suppresses the gene expression of MMPs, − which are involved in the degradation of ECM.…”