1960
DOI: 10.2337/diab.9.6.447
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Effects of Insulin on Blood Glucose Entry and Removal Rates in Man

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Cited by 12 publications
(4 citation statements)
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“…This recycled label is indistinguishable from the original by the GC/C/IRMS technique. Although estimates of the contribution of recycled material to plasma glucose concentration have been made,15–17 these have been in the fasted state, and it is not expected that these estimates are valid under the conditions of the IVGTT. The evidence from this study is that, for the purposes of comparing the two tracers used, recycling mechanisms are not important.…”
Section: Resultsmentioning
confidence: 99%
“…This recycled label is indistinguishable from the original by the GC/C/IRMS technique. Although estimates of the contribution of recycled material to plasma glucose concentration have been made,15–17 these have been in the fasted state, and it is not expected that these estimates are valid under the conditions of the IVGTT. The evidence from this study is that, for the purposes of comparing the two tracers used, recycling mechanisms are not important.…”
Section: Resultsmentioning
confidence: 99%
“…Lactate is probably the most important product of glucose catabolism that is not exclusively intracellular, and its importance as a source for recycling glucose carbon in monogastric animals has been demonstrated (Reichard et al 1963;Waterhouse and Keilson 1969;Forbath and Hetenyi 1970). In fed sheep, lactate carbon enters the oxaloacetate pool in the liver along with substantial quantities of carbon from propionate and amino acids (Bergman, Roe, and Kon 1966;Leng, Steel, and Luick 1967;Judson and Leng 1968;Reilly and Ford 1971).…”
Section: Discussionmentioning
confidence: 99%
“…EGP under basal conditions has been estimated by tracer techniques and by transhepatic catheterization studies (4,5,(8)(9)(10)(11)(12)(13)(39)(40)(41). Studies on the effect of insulin on glucose production have been complicated (a) by hypoglycemia and release of counterregulatory hormones when exogenous insulin has been administered or (b) by hyperglycemia when glucose has been administered as a stimulus to endogenous insulin release.…”
Section: Discussionmentioning
confidence: 99%