Effects of inspiratory muscle-training intensity on cardiovascular control in amateur cyclists

Abreu, Raphael Martins de; Porta, Alberto; Rehder-Santos, Patrícia; Cairo, Beatrice; Silva, Claudio Donisete da; Signini, Étore De Favari; Sakaguchi, Camila A.; Catai, Aparecida Maria

doi:10.1152/ajpregu.00167.2019

Cited by 16 publications

(17 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, in 1 subject belonging to the CIP group the signals were of poor quality, thus allowing the analysis of the recordings of 9, 10, and 11 subjects in the SHAM, MIP60 and CIP groups respectively. The SHAM, MIP60 and CIP groups were similar in terms of age, body mass index, peak VO 2 , MIP and MEP as tested via one-way analysis of variance, or Kruskal-Wallis one-way analysis of variance on ranks when appropriate, applied to continuous variables, or χ 2 test applied to aerobic functional classification (Martins de Abreu et al, 2019).…”

Section: Imt Protocolmentioning

confidence: 99%

A Transfer Entropy Approach for the Assessment of the Impact of Inspiratory Muscle Training on the Cardiorespiratory Coupling of Amateur Cyclists

et al. 2020

Self Cite

View full text Add to dashboard Cite

The strength of cardiorespiratory interactions diminishes with age. Physical exercise can reduce the rate of this trend. Inspiratory muscle training (IMT) is a technique capable of improving cardiorespiratory interactions. This study evaluates the effect of IMT on cardiorespiratory coupling in amateur cyclists. Thirty male young healthy cyclists underwent a sham IMT of very low intensity (SHAM, n = 9), an IMT of moderate intensity at 60% of the maximal inspiratory pressure (MIP60, n = 10) and an IMT of high intensity at the critical inspiratory pressure (CIP, n = 11). Electrocardiogram, non-invasive arterial pressure, and thoracic respiratory movement (RM) were recorded before (PRE) and after (POST) training at rest in supine position (REST) and during active standing (STAND). The beat-to-beat series of heart period (HP) and systolic arterial pressure (SAP) were analyzed with the RM signal via a traditional non-causal approach, such as squared coherence function, and via a causal model-based transfer entropy (TE) approach. Cardiorespiratory coupling was quantified via the HP-RM squared coherence at the respiratory rate (K 2 HP−RM), the unconditioned TE from RM to HP (TE RM→HP) and the TE from RM to HP conditioned on SAP (TE RM→HP|SAP). In PRE condition we found that STAND led to a decrease of TE RM→HP|SAP. After SHAM and CIP training this tendency was confirmed, while MIP60 inverted it by empowering cardiorespiratory coupling. This behavior was observed in presence of unvaried SAP mean and with usual responses of the baroreflex control and HP mean to STAND. TE RM→HP and K 2 HP−RM were not able to detect the post-training increase of cardiorespiratory coupling strength during STAND, thus suggesting that conditioning out SAP is important for the assessment

show abstract

Section: Imt Protocolmentioning

confidence: 99%

A Transfer Entropy Approach for the Assessment of the Impact of Inspiratory Muscle Training on the Cardiorespiratory Coupling of Amateur Cyclists

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Importantly, these indices were calculated during stable blood pressure levels (Parati et al, 1995). In addition, inspiratory muscle training for 11 weeks with the same load used in our study (60% of PImax) determined improved cardiac vagal control in amateur cyclists (Martins de Abreu et al, 2019).…”

Section: Discussionmentioning

confidence: 88%

Acute inspiratory muscle exercise effect on glucose levels, glucose variability and autonomic control in patients with type 2 diabetes: A crossover randomized trial

Schein

Corrêa

Macedo

et al. 2020

Autonomic Neuroscience

View full text Add to dashboard Cite

Inspiratory muscle exercise (IME) can be an alternative to conventional exercise. We aimed to evaluate the effect of IME on glucose, glucose variability, and autonomic cardiovascular control in type 2 diabetes. Fourteen diabetic subjects were randomly assigned to IME with 2% maximal inspiratory pressure (PImax) or 60% PImax wearing a continuous glucose monitoring system for three days. Glucose variability [glucose variance (VAR), glucose coefficient of variation (CV%), glucose standard deviation (SD), and mean amplitude of glycemic excursions (MAGE)] were evaluated. Glucose reduction was observed in 5 min (60% of PImax 33.2% and 2% of PImax 32.0%), 60 min (60% of PImax 29.6% and 2% of PImax 31.4%) and 120 min (60% of PImax 21.4% and 2% of PImax 24.0%) after IME (vs.1 h before the exercise), with no difference between loads. This reduction in glucose levels was observed in all moments of the IME protocol. Glucose variability was reduced after 12 h and 18 h of the IME (ΔCV: P < 0.001, ΔSD: P < 0.001 and ΔVAR: P < 0.001) for both loads. No difference was found in MAGE (P = 0.594) after IME. Mean arterial pressure and heart rate rose during the exercise session with 60% of PImax. Although sufficiently strong to induce cardiovascular changes, an inspiratory muscle exercise session with 60% of PImax in subjects with type 2 diabetes has failed to induce any significant improvement in glucose, glucose variability and autonomic control, compared to the 2% Plmax exercise session.

show abstract

“…Comprehensive metabolomics-based studies using LC-MS/MS are needed to better define potential chronic metabolite shifts related to a variety of exercise training modalities including IMT. IMT can improve exercise performance, perhaps through alterations in metabolites linked to the metaboreflex [4,5,18] and cardiovascular autonomic modulation [10]. This effect may be captured through a more sensitive metabolomics platform than the one used in this study.…”

Section: Discussionmentioning

confidence: 99%

“…In this method, an additional load is applied to the diaphragm and accessory inspiratory muscles to enhance strength and endurance [7]. IMT may attenuate the metaboreflex [6], in which the accumulation of lactate and other metabolites in the respiratory muscles [8] triggers a sympathetic response causing vasoconstriction in the exercise limbs and early exercise termination [5,9,10]. IMT may reduce perceived breathlessness, lactate accumulation, and peripheral fatigue, and accordingly improve exercise performance [4,5,7].…”

Section: Introductionmentioning

confidence: 99%

“…The physiological benefits of IMT in sports performance have been reported in several studies [4,5,7,10,11], but the underlying metabolic mechanisms remain unclear. This study was designed to investigate the effects of IMT performed at three intensities (low, moderate, and high) on the human serum metabolome of healthy male recreational cyclists.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chronic Influence Of Inspiratory Muscle Training At Different Intensities On The Serum Metabolome

Signini

Sakaguchi

Abreu

et al. 2020

Medicine &Amp; Science in Sports &Amp; Exercise

View full text Add to dashboard Cite

This study investigated the chronic effect of inspiratory muscle training (IMT) on the human serum metabolome in healthy male recreational cyclists. Using a randomized, parallel group design, twenty-eight participants were randomized to three IMT groups: low intensity (LI, n = 7); moderate intensity (MI, n = 10); and high intensity (HI, n = 11). The IMT was performed for 11 weeks. Another group of participants under the same conditions, who did not perform the IMT but participated in all procedures, was included as controls (CG, n = 6). Blood samples were collected one week before and after 11 weeks of IMT and analyzed for metabolite shifts using 1H NMR. Statistical analysis included a 4 (group) × 2 (time) repeated measures ANOVA using the general linear model (GLM), and multivariate principal component analysis (PCA). Untargeted metabolomics analysis of serum samples identified 22 metabolites, including amino acids, lipids, and tricarboxylic acid cycle intermediates. Metabolites shifts did not differ between groups, indicating that IMT at three intensity levels did not alter the serum metabolome relative to the control group. These results reveal novel insights into the metabolic effects of the IMT and are consistent with the results from other studies showing negligible chronic alterations in the serum metabolome in response to physical training.

show abstract

Effects of inspiratory muscle-training intensity on cardiovascular control in amateur cyclists

Cited by 16 publications

References 65 publications

A Transfer Entropy Approach for the Assessment of the Impact of Inspiratory Muscle Training on the Cardiorespiratory Coupling of Amateur Cyclists

A Transfer Entropy Approach for the Assessment of the Impact of Inspiratory Muscle Training on the Cardiorespiratory Coupling of Amateur Cyclists

Acute inspiratory muscle exercise effect on glucose levels, glucose variability and autonomic control in patients with type 2 diabetes: A crossover randomized trial

Chronic Influence Of Inspiratory Muscle Training At Different Intensities On The Serum Metabolome

Contact Info

Product

Resources

About