1997
DOI: 10.1016/s0003-4975(97)00816-3
|View full text |Cite
|
Sign up to set email alerts
|

Effects of Increased ICAM-1 on Reperfusion Injury and Chronic Graft Vascular Disease

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
22
0

Year Published

1999
1999
2014
2014

Publication Types

Select...
6
1
1

Relationship

1
7

Authors

Journals

citations
Cited by 42 publications
(22 citation statements)
references
References 16 publications
0
22
0
Order By: Relevance
“…[36][37][38] Consistent with the decrease of TNF-␣ and IFN-␥ production in cardiac allografts, local overexpression of Bcl-2 resulted in the reduced expression of ICAM-1 and VCAM-1. In addition, Huber et al 39 recently reported that increased Bcl-2 expression on T H 2 cells led to the selective survival of T H 2 cells in the mouse viral myocarditis model.…”
Section: Org Frommentioning
confidence: 70%
“…[36][37][38] Consistent with the decrease of TNF-␣ and IFN-␥ production in cardiac allografts, local overexpression of Bcl-2 resulted in the reduced expression of ICAM-1 and VCAM-1. In addition, Huber et al 39 recently reported that increased Bcl-2 expression on T H 2 cells led to the selective survival of T H 2 cells in the mouse viral myocarditis model.…”
Section: Org Frommentioning
confidence: 70%
“…Up-regulated expression of ICAM-1 has been documented in cardiac myocytes after allotransplantation (16), and this adhesion molecule may play an important role in mediating host immune cell interactions with the donor tissue (19,20). We therefore tested the ability of our ODN delivery system to modulate expression of ICAM-1 in rat hearts during the posttransplantation period.…”
Section: Resultsmentioning
confidence: 99%
“…Hearts were harvested from adult male Sprague-Dawley or PVG rats (Ϸ300 g) after induction of anesthesia with intraperitoneal ketamine (35 mg/kg)/xylazine (7 mg/kg) as described (16). The aortic root was cannulated just before excision, and the coronary circulation was perfused with either Stanford cardioplegia solution or heparinized saline solution (1 unit/ml).…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…23 In addition, treatment with anti-ICAM-1 antibody has been shown to inhibit GCAD in rats. 24 The diseased graft shows abundant ICAM-1, especially on the endothelial surface. 22 These adhesion molecules may facilitate transmigration of inflammatory and immune cells to the graft and contribute to ischemia-reperfusion injury as well as GCAD.…”
Section: Tanaka Et Al Effects Of Superoxide Dismutase 1 On Cardiac Grmentioning
confidence: 99%