Two separate performance trials were conducted to determine the effects of postpelleting feed or drinking water application of a Lactobacillus-based probiotic, alone or in combination with a phytogenic product, on growth parameters of broilers fed medicated or nonmedicated diets. Trial 1 consisted of 1,000 straight-run broilers that were randomized, placed in floor rearing pens, and fed medicated diets. At the conclusion of the experiment, BW of broilers receiving the probiotic were not different (P > 0.05) when compared with control broilers. In trial 2, stocking densities were increased to simulate local industry rearing practices, resulting in a total placement of 1,880 chicks in the same rearing facility. Broilers in trial 2 were fed nonmedicated diets. Broilers administered the probiotic by intermittent drinking water application had increased (P < 0.05) BW and improved FCR (P < 0.05) through d 40 compared with control birds. Similarly, broilers receiving the phytogenic product had reduced (P < 0.05) FCR at d 40 compared with control broilers. We conclude that probiotic administration, alone or in combination with a phytogenic product, has the potential to influence broiler performance during commercial grow-out.