Effects of imidacloprid, a neonicotinoid insecticide, on the echolocation system of insectivorous bats

Wu, Chung Hsin; Lin, Ching Lung; Wang, Sheue Er; Lu, Chen Wen

doi:10.1016/j.pestbp.2019.10.010

Cited by 31 publications

(33 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Consequently, B. aeneus has developed high levels of resistance to pyrethroid insecticides in several areas across Europe (Slater et al 2011;Heimbach and Müller 2013;Zamojska 2017;Stará and Kocourek 2018;Kaiser et al 2018). While neonicotinoid insecticides are also being applied in B. aeneus management (Seidenglanz et al 2017;Kaiser et al 2018), exposure to neonicotinoids has shown negative effects on a wide range of nontarget organisms (Gibbons et al 2015;Pisa et al 2017;Willow et al 2019;Berheim et al 2019;Calvo-Agudo et al 2019;Wu et al 2019). For example, in oilseed rape agroecosystems, nontarget organisms negatively affected by thiacloprid applications could include economically important parasitoids of B. aeneus, given that laboratory studies have demonstrated the detrimental effect of thiacloprid on other parasitoid wasps (Sugiyama et al 2011;Jans 2012;Willow et al 2019).…”

Section: Introductionmentioning

confidence: 99%

Targeting a coatomer protein complex-I gene via RNA interference results in effective lethality in the pollen beetle Brassicogethes aeneus

et al. 2020

View full text Add to dashboard Cite

The pollen beetle Brassicogethes aeneus is a serious pest of oilseed rape (Brassica napus) in Europe. Management of this pest has grown difficult due to B. aeneus’s development of resistance to pyrethroid insecticides, as well as the pressure to establish control strategies that minimise the impact on nontarget organisms. RNA interference represents a nucleotide sequence-based, and thus potentially species-specific, approach to agricultural pest control. The present study examined the efficacy of targeting the coatomer gene coatomer subunit alpha (αCOP), via both microinjection and dietary exposure to exogenous complementary dsRNA, on αCOP-silencing and subsequent mortality in B. aeneus. Beetles injected with dsRNA targeting αCOP (at 0.14 µg/mg) showed 88% and 100% mortality at 6 and 10 days post-injection, respectively; where by the same time after dietary exposure, 43%–89% mortality was observed in the 3 µg dsRNA/µL treatment, though the effect was concentration-dependent. Thus, the effect was significant for both delivery routes. In working towards RNA-based management of B. aeneus, future studies should include αCOP as a target of interest.

show abstract

Section: Introductionmentioning

confidence: 99%

Targeting a coatomer protein complex-I gene via RNA interference results in effective lethality in the pollen beetle Brassicogethes aeneus

et al. 2020

View full text Add to dashboard Cite

show abstract

“…There is a lot of evidence that imidacloprid has the potential to adversely impact ecosystems and human health. For instance, it was gradually discovered that imidacloprid is toxic to humans, and that imidacloprid is lethal to non-target organisms such as bats, earthworms, bees, fish, and shrimp (Table 1) [17][18][19][20][21]. Inhibits thyroid hormone secretion, causes abnormal alignment of the spermatogenic epithelium, epididymal hyperplasia, and oligospermia in male lizards [28][29][30] 7.…”

Section: Toxicity Of Imidaclopridmentioning

confidence: 99%

“…Imidacloprid has also been shown to disrupt blood glucose regulation in developing and adult rats through hyperglycemic activity [18]. Imidacloprid has further been shown to interfere with the echolocation system of insect-eating bats; after imidacloprid poisoning, insect-eating bats may reduce the expression of auditory related proteins in the cochlea, the expression of sound-related FOXP2 in the superior colliculus, and the expression of auditory related otoferlin in the cochlea and lower colliculus, thus causing inflammation and cell apoptosis associated with mitochondrial dysfunction in the hippocampus and medial entorhinal cortex [19].…”

Section: Toxicity To Humans and Terrestrial Animalsmentioning

confidence: 99%

“…Neonicotinoid pesticides have led to a global decline in bee populations [19]. More and more research has documented the direct and indirect effects of imidacloprid insecticides on pollinators.…”

Section: Toxicity To Insectsmentioning

confidence: 99%

Section: Toxicity Of Imidaclopridmentioning

confidence: 99%

See 2 more Smart Citations

Insights into the Toxicity and Degradation Mechanisms of Imidacloprid Via Physicochemical and Microbial Approaches

Pang

Lin

Zhang

et al. 2020

Toxics

View full text Add to dashboard Cite

Imidacloprid is a neonicotinoid insecticide that has been widely used to control insect pests in agricultural fields for decades. It shows insecticidal activity mainly by blocking the normal conduction of the central nervous system in insects. However, in recent years, imidacloprid has been reported to be an emerging contaminant in all parts of the world, and has different toxic effects on a variety of non-target organisms, including human beings, due to its large-scale use. Hence, the removal of imidacloprid from the ecosystem has received widespread attention. Different remediation approaches have been studied to eliminate imidacloprid residues from the environment, such as oxidation, hydrolysis, adsorption, ultrasound, illumination, and biodegradation. In nature, microbial degradation is one of the most important processes controlling the fate of and transformation from imidacloprid use, and from an environmental point of view, it is the most promising means, as it is the most effective, least hazardous, and most environmentally friendly. To date, several imidacloprid-degrading microbes, including Bacillus, Pseudoxanthomonas, Mycobacterium, Rhizobium, Rhodococcus, and Stenotrophomonas, have been characterized for biodegradation. In addition, previous studies have found that many insects and microorganisms have developed resistance genes to and degradation enzymes of imidacloprid. Furthermore, the metabolites and degradation pathways of imidacloprid have been reported. However, reviews of the toxicity and degradation mechanisms of imidacloprid are rare. In this review, the toxicity and degradation mechanisms of imidacloprid are summarized in order to provide a theoretical and practical basis for the remediation of imidacloprid-contaminated environments.

show abstract

Aquatic‐Terrestrial Insecticide Fluxes: Midges as Neonicotinoid Vectors

Roodt

Schaufelberger

Schulz

2022

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Exposure of freshwater ecosystems to insecticides can negatively impact the development of emerging aquatic insects. These insects serve as an important nutritional subsidy for terrestrial insectivores. Changes in insect emergence phenology (i.e., emergence success and temporal pattern) or fluxes of insecticides retained by the emerging adults have the potential to negatively impact terrestrial food webs. These processes are influenced by contaminant toxicity, lipohilicity, or metabolic processes. The interplay between emergence phenology, contaminant retention through metamorphosis, and associated contaminant flux is not yet understood for current-use insecticides. In a microcosm study, we evaluated the impacts of a 24-h pulse exposure of one of three current-use insecticides, namely pirimicarb, indoxacarb, and thiacloprid, at two environmentally realistic concentration levels on the larval development and emergence of the nonbiting midge Chironomus riparius. In addition, we measured insecticide concentrations in the larvae and adults using ultrahigh performance liquid chromatography coupled to tandem mass spectrometry by electrospray ionization. Exposure to pirimicarb delayed larval development and emergence, and exposure to indoxacarb reduced emergence success. The neonicotinoid thiacloprid had the greatest impact by reducing larval survival and emergence success. At the same time, thiacloprid was the only insecticide measured in the adults with average concentrations of 10.3 and 37.3 ng/g after exposure at 0.1 and 4 µg/L, respectively. In addition, an approximate 30% higher survival to emergence after exposure to 0.1 µg/L relative to a 4-µg/L exposure resulted in a relatively higher flux of thiacloprid, from the aquatic to the terrestrial environment, at the lower exposure. Our experimental results help to explain the impacts of current-use insecticides on aquatic-terrestrial subsidy coupling and indicate the potential for widespread dietary exposure of terrestrial insectivores preying on emerging aquatic insects to the neonicotinoid thiacloprid.

show abstract

Effects of imidacloprid, a neonicotinoid insecticide, on the echolocation system of insectivorous bats

Cited by 31 publications

References 41 publications

Targeting a coatomer protein complex-I gene via RNA interference results in effective lethality in the pollen beetle Brassicogethes aeneus

Targeting a coatomer protein complex-I gene via RNA interference results in effective lethality in the pollen beetle Brassicogethes aeneus

Insights into the Toxicity and Degradation Mechanisms of Imidacloprid Via Physicochemical and Microbial Approaches

Aquatic‐Terrestrial Insecticide Fluxes: Midges as Neonicotinoid Vectors

Contact Info

Product

Resources

About