“…Previous studies have shown that changes in sensitivity on the order of 10%–20% between projections (due to both lag and ghosting) begin to introduce artifacts into reconstructed images; however, an investigation of the effects of lag and ghosting of the order observed here (< 0.5% and < 3.5%, respectively) is beyond the scope of this study, but is presumed to be comparable to temporal effects in conventional DBT systems. However, since the exposures studied here correspond to detector exposures typical behind and outside an average breast, the temporal characteristics observed are thought to be representative of clinical practice, and thus expected to have little impact on image quality.…”