2021
DOI: 10.1101/2021.05.07.443070
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Effects ofPlatycodon grandiflorumon Gut Microbiota and Immune System of Immunosuppressed Mouse

Abstract: Platycodon grandiflorum (PG) has been used as a traditional remedy to control immune related diseases. However, there is limited information about its immune stimulating effects on the immunosuppressed model. The main bioactive components such as saponins are known to con-tribute to controlling immune activity. Thus, we developed an aged red PG (PGS) with 2.6 times of platycodin D, one of the saponins. We treated PG and PGS (PG-diets) to immunosuppressed mice via cyclophosphamide (CPA) injection. After 2weeks… Show more

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